Evidence map›Paper›PMID 38156308›Full record

ArticleIranian journal of microbiology2023

Detection of FOX-AmpC-β-lactamase gene and antibiogram of AmpC-beta-lactamase-producing pathogens isolated from chronic suppurative otitis media patients in Nigeria.

Ibiam Francis Amadi, Obasikene Catherine Nchedo, Ariom Thaddaeus Obaji, Monday Agbonifo, Egwu Eze, Iroha Chidinma Stacy, Moses Ikechukwu Benjamin, Iroha Ifeanyichukwu Romanus

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In one paragraph

Article in Iranian journal of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Ibiam Francis AmadiDepartment of Otorhinolaryngology, Alex Ekwueme Federal University, Ndufu Alike Ikwo, Nigeria.
Obasikene Catherine NchedoDepartment of Radiology, Nnamdi Azikiwe University, Awka, Nigeria.
Ariom Thaddaeus ObajiDepartment of Microbiology, Institute of Food Security, Environmental Resources and Agricultural Research, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria.
Monday AgbonifoDepartment of Otorhinolaryngology, Ambrose Ali University, Ekpoma, Nigeria.
Egwu EzeDepartment of Medical Laboratory Science, Alex Ekwueme Federal University, Teaching Hospital Abakaliki, Nigeria.
Iroha Chidinma StacyDepartment of Pharmacy, Alex Ekwueme Federal University, Teaching Hospital, Abakaliki, Nigeria.
Moses Ikechukwu BenjaminDepartment of Applied Microbiology, Faculty of Sciences, Ebonyi State University, Abakaliki, Nigeria.
Iroha Ifeanyichukwu RomanusDepartment of Applied Microbiology, Faculty of Sciences, Ebonyi State University, Abakaliki, Nigeria.
Ebonyi State University · NGFederal Teaching Hospital Abakaliki · NGAlex Ekwueme Federal University, Ndufu-AlikeAmbrose Alli University · NGFederal University of Agriculture · NGNnamdi Azikiwe University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: AmpC-producing Gram-negative bacterial (GNB) pathogens are distributed worldwide, especially in clinical settings. This study aimed to determine the antibiogram and the type of AmpC-β-lactamase gene harboured by GNB pathogens implicated in chronic suppurative otitis media (CSOM) cases. Materials and Methods: Ear swab samples (300) collected from patients with active CSOM were analysed using standard microbiological techniques. Phenotypic and molecular detection of AmpC β-lactamase production was done by cefoxitin/cloxacillin double-disk synergy test and PCR respectively. Antibiogram was determined by disk diffusion technique. Results: Among the GNB pathogens isolated from CSOM patients, Conclusion: The detection of AmpC β-lactamase-producing multidrug-resistant GNB pathogens harbouring FOX-AmpC-β-lactamase gene among patients with CSOM infections in our study is a serious public health problem which needs urgent intervention.

Indexed as

AmpC-β-lactamaseChronic suppurative otitis mediaFOX-AmpC geneGram-negative bacterial pathogensMultidrug resistance

Identifiers

PMID38156308
PMCPMC10751608
OpenAlexW4389057650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.