Evidence map›Paper›PMID 38156087›Full record

ArticleFrontiers in neurology2023

Stroke classification and treatment support system artificial intelligence for usefulness of stroke diagnosis.

Nobukazu Miyamoto, Yuji Ueno, Kazuo Yamashiro, Kenichiro Hira, Chikage Kijima, Naoki Kitora, Yoshihiko Iwao, Kayo Okuda, Shohei Mishima, Daisuke Takahashi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Nobukazu MiyamotoDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Yuji UenoDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Kazuo YamashiroDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Kenichiro HiraDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Chikage KijimaDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Naoki KitoraHACARUS INC., Kyoto, Japan.
Yoshihiko IwaoHACARUS INC., Kyoto, Japan.
Kayo OkudaHACARUS INC., Kyoto, Japan.
Shohei MishimaHACARUS INC., Kyoto, Japan.
Daisuke TakahashiHACARUS INC., Kyoto, Japan.
Kazuto OnoOhara Pharmaceutical Co., Ltd., Tokyo, Japan.
Mika AsariPARKINSON Laboratories Co., Ltd., Tokyo, Japan.
Kazuki MiyazakiPARKINSON Laboratories Co., Ltd., Tokyo, Japan.
Nobutaka HattoriDepartment of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: It is important to diagnose cerebral infarction at an early stage and select an appropriate treatment method. The number of stroke-trained physicians is unevenly distributed; thus, a shortage of specialists is a major problem in some regions. In this retrospective design study, we tested whether an artificial intelligence (AI) we built using computer-aided detection/diagnosis may help medical physicians to classify stroke for the appropriate treatment. Methods: To build the Stroke Classification and Treatment Support System AI, the clinical data of 231 hospitalized patients with ischemic stroke from January 2016 to December 2017 were used for training the AI. To verify the diagnostic accuracy, 151 patients who were admitted for stroke between January 2018 and December 2018 were also enrolled. Results: By utilizing multimodal data, such as DWI and ADC map images, as well as patient examination data, we were able to construct an AI that can explain the analysis results with a small amount of training data. Furthermore, the AI was able to classify with high accuracy (Cohort 1, evaluation data 88.7%; Cohort 2, validation data 86.1%). Conclusion: In recent years, the treatment options for cerebral infarction have increased in number and complexity, making it even more important to provide appropriate treatment according to the initial diagnosis. This system could be used for initial treatment to automatically diagnose and classify strokes in hospitals where stroke-trained physicians are not available and improve the prognosis of cerebral infarction.

Indexed as

cerebral infarctionk-Nearest Neighbor methodleave-one-out cross-validation methodmultimodal artificial intelligencestrokeTOAST classification

Identifiers

PMID38156087
PMCPMC10753815
OpenAlexW4389729049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.