Evidence map›Paper›PMID 38155876›Full record

Article... International Conference on Wearable and Implantable Body Sensor Networks. International Conference on Wearable and Implantable Body Sensor Networks2023

Preliminary feasibility of a wrist-worn receiver to measure medication adherence via an ingestible radiofrequency sensor.

Charlotte E Goldfine, Hannah Albrechta, Conall O'Cleirigh, Adam Standley, Yassir Mohamed, Joanne Hokayem, Jasper S Lee, T Christopher Carnes, Georgia R Goodman, Kenneth H Mayer and 2 more

Open access · greenAbstract read
In one paragraph

Article in ... International Conference on Wearable and Implantable Body Sensor Networks. International Conference on Wearable and Implantable Body Sensor Networks, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Charlotte E GoldfineDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, USA.
Hannah AlbrechtaThe Fenway Institute, Boston, USA.
Conall O'CleirighDepartment of Psychiatry, Massachusetts General Hospital, Boston, USA.
Adam StandleyetectRx, Gainesville, USA.
Yassir MohamedThe Fenway Institute, Boston, USA.
Joanne HokayemThe Fenway Institute, Boston, USA.
Jasper S LeeDepartment of Psychiatry, Massachusetts General Hospital, Boston, USA.
T Christopher CarnesetectRx, Gainesville, USA.
Georgia R GoodmanDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, USA.
Kenneth H MayerThe Fenway Institute, Boston, USA.
Pamela AlpertetectRx, Gainesville, USA.
Peter R ChaiDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, USA.
Fenway Health · USBrigham and Women's Hospital · USBoston University · USMassachusetts General Hospital · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Smart Steps: A context-aware adherence intervention to improve PrEP adherence among men who have sex with men (MSM) with substance use disorderDP2DA056107 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2022 to 2022
$2.7M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
ID-Cap System: Next generation ingestible sensors for medication adherence measurementR43NR020289 · NINR · ETECTRX, INC. · PI CARNES, TONY CHRIS, CHAI, PETER R · 2022 to 2022
$259k
NIAID NIH HHS P30 AI060354NIDA NIH HHS DP2 DA056107NIDA NIH HHS K23 DA044874NINR NIH HHS R43 NR020289
6 · The paper itself

Abstract

Adherence to medications is a complex task that requires complex biobehavioral support. To better provide tools to assist with medication adherence, digital pills provide an option to directly measure medication taking behaviors. These systems comprise a gelatin capsule with radiofrequency emitter, a wearable Reader that collects the radio signal and a smartphone app that collects ingestion data displays it for patients and clinicians. These systems are feasible in measuring adherence in the real-world, even in stigmatized diseases like HIV treatment adherence. While the current iteration of the digital pill system utilizes a wearable Reader worn like a necklace, preliminary feedback demonstrated that a miniaturized system that was worn on the wrist could be more functional in the real-world. This paper therefore describes the development and preliminary field testing of a wrist-borne wearable Reader to facilitate acquisition of oral HIV pre-exposure prophylaxis (PrEP) adherence data among individual prescribed PrEP.

Indexed as

ingestible sensormedication adherenceradiofrequency

Identifiers

PMID38155876
PMCPMC10753620
OpenAlexW4389230807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.