Evidence map›Paper›PMID 38155597›Full record

ArticleOrganic letters2023

Total Synthesis of the Reported Structure of Cahuitamycin A: Insights into an Elusive Natural Product Scaffold.

Justin A Shapiro, Savannah J Post, Gavin C Smith, William M Wuest

Open access · hybridAbstract read
In one paragraph

Article in Organic letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Justin A ShapiroDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0001-9891-0464
Savannah J PostDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Gavin C SmithDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
William M WuestDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0002-5198-7744
Emory University · US

Funding

Natural Product-Inspired Approaches Toward The Development Of Antivirulence And Species-Specific InhibitorsR35GM119426 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI William M Wuest · 2016 to 2026
$4.8M
Diverted Total Synthesis and Biological Evaluation of Natural Product Biofilm Inhibitors, The CahuitamycinsF32GM133091 · NIGMS · EMORY UNIVERSITY · PI SHAPIRO, JUSTIN A. · 2019 to 2020
$109k
NIGMS NIH HHS F32 GM133091NIGMS NIH HHS R35 GM119426
6 · The paper itself

Abstract

In a 2016 screen of natural product extracts, a new family of natural products, the cahuitamycins, was discovered and found to inhibit biofilm formation in the human pathogen

Indexed as

Acinetobacter baumanniiBiological ProductsHumansIsomerismMolecular StructureStereoisomerismBiological Products

Identifiers

PMID38155597
PMCPMC10758118
OpenAlexW4389889658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.