Evidence map›Paper›PMID 38155248›Full record

ArticleScientific reports2023

Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay.

Jonathan Burnie, Claire Fernandes, Deepa Chaphekar, Danlan Wei, Shubeen Ahmed, Arvin Tejnarine Persaud, Nawrah Khader, Claudia Cicala, James Arthos, Vera A Tang and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06889142 (Proof-of-Concept Study), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06889142 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Proof-of-Concept Study: Investigating the Impact of NMN Supplementation on CD4+ T Cell Recovery in Virologically Suppressed HIV Patients With Immunological Failure

TypeinterventionalSponsorTriHealth Inc.Ran2025 to 2025Enrolled7ConditionsHuman Immunodeficiency VirusArmsNicotinamide Mononucleotide
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jonathan BurnieDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada.
Claire FernandesDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada.
Deepa ChaphekarDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada.
Danlan WeiLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Shubeen AhmedDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada.
Arvin Tejnarine PersaudDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada.
Nawrah KhaderDepartment of Cell and Systems Biology, University of Toronto, 25 Harbord Street, Toronto, ON, Canada.
Claudia CicalaLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
James ArthosLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Vera A TangFlow Cytometry and Virometry Core Facility, Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, Canada.
Christina GuzzoDepartment of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada. christina.guzzo@utoronto.ca.
University of Toronto · CANational Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USUniversity of Ottawa · CA

Funding

CIHR Michael Smith Foreign Study SupplementsCIHR PJH 175379
6 · The paper itself

Abstract

While numerous cellular proteins in the HIV envelope are known to alter virus infection, methodology to rapidly phenotype the virion surface in a high throughput, single virion manner is lacking. Thus, many human proteins may exist on the virion surface that remain undescribed. Herein, we developed a novel flow virometry screening assay to discover new proteins on the surface of HIV particles. By screening a CD4

Indexed as

HIV InfectionsVirusesCell LineHumansVirion

Identifiers

PMID38155248
PMCPMC10754950
OpenAlexW4390339733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.