Evidence map›Paper›PMID 38154992›Full record

ArticleVaccine2024

Costs of seasonal influenza vaccine delivery in a pediatric demonstration project for children aged 6-23 months - Nakuru and Mombasa Counties, Kenya, 2019-2021.

Radhika Gharpure, Angela Oloo Akumu, Jeanette Dawa, Stacie Gobin, Bishwa B Adhikari, Kathryn E Lafond, Leah S Fischer, Harriet Mirieri, Henry Mwazighe, Collins Tabu and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 3 countries.

Radhika GharpureU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: rgharpure@cdc.gov.
Angela Oloo AkumuWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Jeanette DawaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Stacie GobinGobin Global, LLC, Asheville, NC, USA; Partnership for Influenza Vaccine Introduction, Task Force for Global Health, Atlanta, GA, USA.
Bishwa B AdhikariU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Kathryn E LafondU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Leah S FischerU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Harriet MirieriWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Henry MwazigheWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Collins TabuNational Vaccines and Immunization Program, Ministry of Health, Kenya.
Rose Jalang'oNational Vaccines and Immunization Program, Ministry of Health, Kenya.
Peter KamauNational Vaccines and Immunization Program, Ministry of Health, Kenya.
Catherine SilaliNational Vaccines and Immunization Program, Ministry of Health, Kenya.
Rosalia KalaniDivision of Disease Surveillance and Response, Ministry of Health, Kenya.
Pauline OgingaDepartment of Health, Mombasa County, Kenya.
Isaac JewaDepartment of Health, Mombasa County, Kenya.
Virginia NjengaDepartment of Health, Nakuru County, Kenya.
Malembe S EbamaPartnership for Influenza Vaccine Introduction, Task Force for Global Health, Atlanta, GA, USA.
Joseph S BreseePartnership for Influenza Vaccine Introduction, Task Force for Global Health, Atlanta, GA, USA.
M Kariuki NjengaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya; Paul G. Allen School of Global Health, Washington State University (WSU), Pullman, WA, USA.
Eric OsoroWashington State University (WSU) Global Health Kenya, Nairobi, Kenya; Paul G. Allen School of Global Health, Washington State University (WSU), Pullman, WA, USA.
Martin I MeltzerU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Gideon O EmukuleU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA; U.S. Centers for Disease Control and Prevention, Nairobi, Kenya.
Washington State Department of Health · USCenters for Disease Control and Prevention · USMinistry of Health · KEThe Task Force for Global Health · USCenters for Disease Control and Prevention · KENakuru County Council · KE

Funding

CGH CDC HHS U01 GH002143Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundDuring November 2019-October 2021, a pediatric influenza vaccination demonstration project was conducted in four sub-counties in Kenya. The demonstration piloted two different delivery strategies: year-round vaccination and a four-month vaccination campaign. Our objective was to compare the costs of both delivery strategies.

methodsCost data were collected using standardized questionnaires and extracted from government and project accounting records. We reported total costs and costs per vaccine dose administered by delivery strategy from the Kenyan government perspective in 2021 US$. Costs were separated into financial costs (monetary expenditures) and economic costs (financial costs plus the value of existing resources). We also separated costs by administrative level (national, regional, county, sub-county, and health facility) and program activity (advocacy and social mobilization; training; distribution, storage, and waste management; service delivery; monitoring; and supervision).

resultsThe total estimated cost of the pediatric influenza demonstration project was US$ 225,269 (financial) and US$ 326,691 (economic) for the year-round delivery strategy (30,397 vaccine doses administered), compared with US$ 214,753 (financial) and US$ 242,385 (economic) for the campaign strategy (25,404 doses administered). Vaccine purchase represented the largest proportion of costs for both strategies. Excluding vaccine purchase, the cost per dose administered was US$ 1.58 (financial) and US$ 5.84 (economic) for the year-round strategy and US$ 2.89 (financial) and US$ 4.56 (economic) for the campaign strategy.

conclusionsThe financial cost per dose was 83% higher for the campaign strategy than the year-round strategy due to larger expenditures for advocacy and social mobilization, training, and hiring of surge staff for service delivery. However, the economic cost per dose was more comparable for both strategies (year-round 22% higher than campaign), balanced by higher costs of operating equipment and monitoring activities for the year-round strategy. These delivery cost data provide real-world evidence to inform pediatric influenza vaccine introduction in Kenya.

Indexed as

Immunization ProgramsInfluenza, HumanInfluenza VaccinesVaccinationFemaleHumansInfantKenyaMaleSeasonsInfluenza VaccinesEconomicsExpendituresInfluenza vaccinePediatricVaccination

Identifiers

PMID38154992
PMCPMC11702309
OpenAlexW4390277333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.