Evidence map›Paper›PMID 38154933›Full record

Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2024

E-health intervention for preventing recurrent ankle sprains: a randomised controlled trial in general practice.

Adinda Ke Mailuhu, Evert Alm Verhagen, John van Ochten, Patrick Je Bindels, Sita Ma Bierma-Zeinstra, Marienke van Middelkoop

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Selection and reporting of usual care comparators when designing primary care trials of complex health interventions: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adinda Ke MailuhuDepartment of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-8504-9273
Evert Alm VerhagenDepartment of Health Sciences & EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.ORCID 0000-0001-9227-8234
John van OchtenDepartment of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-8468-2325
Patrick Je BindelsDepartment of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-5941-4820
Sita Ma Bierma-ZeinstraDepartment of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0003-1280-5896
Marienke van MiddelkoopDepartment of General Practice, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-6926-0618

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnkle sprains are frequent injuries in general practice. However, no effective treatment is available yet.

aimTo examine the effectiveness of an unsupervised e-health-supported neuromuscular training programme in combination with usual care compared with usual care alone in patients with acute lateral ankle sprains in general practice. DESIGN AND

settingRandomised controlled trial with 1-year follow-up among patients (14-65 years) who visited the GP with an acute lateral ankle sprain within 3 weeks of injury.

methodThe intervention group received, in addition to usual care, an unsupervised e-health-supported neuromuscular training programme and the control group received usual care alone. The primary outcome was self-reported re-sprains during 52 weeks of follow-up. Secondary outcomes were ankle function, pain in rest and during activity, subjective recovery, and return to the same type and level of sport.

resultsIn total, 165 participants (mean age 38.3 years and 69 [41.8%] male) were included. No statistically significant difference in the occurrence of a re-sprain were found between the intervention 20.7% (17/82) and control group 24.1% (20/83) (hazard ratio 1.14, 95% confidence interval = 0.59 to 2.21). Also, no statistically significant differences in secondary outcomes were found between groups. The adherence rate to the programme was low (6.1%, 5/82).

conclusionThe rate of re-sprains was relatively high and an unsupervised e-health-supported neuromuscular training programme does not yield meaningful effects and does not encourage adherence in preventing re-sprains in patients in general practice. More research is necessary to indicate the best treatment modality and way of delivery for these patients.

Indexed as

Ankle InjuriesGeneral PracticeSprains and StrainsTelemedicineAdultFamily PracticeFemaleHumansMaleankle sprainse-healthgeneral practiceneuromuscular trainingtreatment

Identifiers

PMID38154933
PMCPMC10755994

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.