Evidence map›Paper›PMID 38154885›Full record

ArticleBMJ open2023

Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study.

Jingyan Yang, Kathleen Michelle Andersen, Kiran K Rai, Theo Tritton, Tendai Mugwagwa, Maya Reimbaeva, Carmen Tsang, Leah J McGrath, Poppy Payne, Bethany Emma Backhouse and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Jingyan YangPfizer Inc, New York, New York, USA jingyan.yang@pfizer.com.
Kathleen Michelle AndersenPfizer Inc, New York, New York, USA.ORCID 0000-0003-2670-800X
Kiran K RaiAdelphi Real World, Bollington, UK.
Theo TrittonAdelphi Real World, Bollington, UK.
Tendai MugwagwaPfizer Inc, New York, New York, USA.
Maya ReimbaevaPfizer Inc, New York, New York, USA.
Carmen TsangPfizer, Tadworth, UK.
Leah J McGrathPfizer Inc, New York, New York, USA.
Poppy PayneAdelphi Real World, Bollington, UK.
Bethany Emma BackhouseAdelphi Real World, Bollington, UK.ORCID 0000-0001-6114-660X
Diana MendesPfizer, Tadworth, UK.
Rebecca ButfieldPfizer, Tadworth, UK.
Kevin NaickerPfizer, Tadworth, UK.
Mary AraghiPfizer, Tadworth, UK.
Robert WoodAdelphi Real World, Bollington, UK.ORCID 0000-0002-6977-435X
Jennifer L NguyenPfizer Inc, New York, New York, USA.
Pfizer (United States) · USAdelphi Group (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo quantify direct costs and healthcare resource utilisation (HCRU) associated with acute COVID-19 in adults in England.

designPopulation-based retrospective cohort study using Clinical Practice Research Datalink Aurum primary care electronic medical records linked to Hospital Episode Statistics secondary care administrative data.

settingPatients registered to primary care practices in England. POPULATION: 1 706 368 adults with a positive SARS-CoV-2 PCR or antigen test from August 2020 to January 2022 were included; 13 105 within the hospitalised cohort indexed between August 2020 and March 2021, and 1 693 263 within the primary care cohort indexed between August 2020 and January 2022. Patients with a COVID-19-related hospitalisation within 84 days of a positive test were included in the hospitalised cohort.

main outcome measuresPrimary and secondary care HCRU and associated costs ≤4 weeks following positive COVID-19 test, stratified by age group, risk of severe COVID-19 and immunocompromised status.

resultsAmong the hospitalised cohort, average length of stay, including critical care stays, was longer in older adults. Median healthcare cost per hospitalisation was higher in those aged 75-84 (£8942) and ≥85 years (£8835) than in those aged <50 years (£7703). While few (6.0%) patients in critical care required mechanical ventilation, its use was higher in older adults (50-74 years: 8.3%; <50 years: 4.3%). HCRU and associated costs were often greater in those at higher risk of severe COVID-19 than in the overall cohort, although minimal differences in HCRU were found across the three different high-risk definitions. Among the primary care cohort, general practitioner or nurse consultations were more frequent among older adults and the immunocompromised.

conclusionsCOVID-19-related hospitalisations in older adults, particularly critical care stays, were the primary drivers of high COVID-19 resource use in England. These findings may inform health policy decisions and resource allocation in the prevention and management of COVID-19.

Indexed as

COVID-19AgedCohort StudiesDelivery of Health CareEnglandHospitalizationHumansPrimary Health CareRetrospective StudiesSARS-CoV-2COVID-19HospitalizationPrimary Health CareRetrospective Studies

Identifiers

PMID38154885
PMCPMC10759085
OpenAlexW4390350817

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.