Evidence map›Paper›PMID 38154880›Full record

ArticleBMJ open2023

Characterisation of internal tremors and vibration symptoms.

Dorothy Massey, Mitsuaki Sawano, Anna D Baker, Diana Berrent Güthe, Nick Güthe, Suzanne Pincus Shidlovsky, Liza Fisher, Connor B Grady, Cesar Caraballo, Tianna Zhou and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Neuroimmune pathophysiology of long COVID.Psychiatry and clinical neurosciences · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dorothy MasseyCenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA.
Mitsuaki SawanoCenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA.ORCID 0000-0003-2789-1758
Anna D BakerSection of Stroke and Vascular Neurology, Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.
Diana Berrent GütheSurvivor Corps, Washington, DC, Washington, USA.
Nick GütheSurvivor Corps, Washington, DC, Washington, USA.
Suzanne Pincus ShidlovskySurvivor Corps, Washington, DC, Washington, USA.
Liza FisherSurvivor Corps, Washington, DC, Washington, USA.
Connor B GradyDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Cesar CaraballoCenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-4557-9437
Tianna ZhouYale School of Medicine, New Haven, Connecticut, USA.
Richa SharmaDepartment of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA harlan.krumholz@yale.edu.ORCID 0000-0003-2046-127X

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectivesTo describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belonging to its Facebook group with a history of COVID-19 suffering from vibrations and tremors. SETTING AND

designA narrative analysis was performed on 140 emails and 450 social media comments from 140 individuals collected as a response to a call to >180 000 individuals participating in Survivor Corps between 15 July and 27 July 2021. We used common coding techniques and the constant comparative method for qualitative data synthesis and categorising emails. Coded data were entered into NVivo V.12 to identify recurrent themes, theme connections and supporting quotations. Comments were analysed using Word Clouds, generated with R V.4.0.3 using

main outcome measuresPatient-reported long COVID symptom themes and domains related to internal tremors and vibration.

resultsThe respondents' emails represented 22 themes and 7 domains pertaining to their experience with internal tremor and vibrations. These domains were as follows: (1) symptom experience, description and anatomic location; (2) initial symptom onset; (3) symptom timing; (4) symptom triggers or alleviators; (5) change from baseline health status; (6) experience with medical establishment and (7) impact on individuals' lives and livelihood. There were 22 themes in total, each corresponding to one of the broader domains. Among the responses, many described symptoms that varied in location, timing and triggers, occurred soon after their COVID-19 infection, and were markedly debilitating. There were often frustrating experiences with the healthcare system.

conclusionsThis study describes key themes and experiences among a group of people reporting long COVID and having a prolonged and debilitating symptom complex that prominently features internal tremors and vibrations.

Indexed as

COVID-19Post-Acute COVID-19 SyndromeDelivery of Health CareHumansTremorVibrationCOVID-19NEUROLOGYREGISTRIES

Identifiers

PMID38154880
PMCPMC10759066

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.