Evidence map›Paper›PMID 38154108›Full record

ArticleAging2023

The peptide Acein promotes dopamine secretion through

Jiaqi Wang, Dong Wang, Sarra Setrerrahmane, Jean Martinez, Han-Mei Xu

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jiaqi WangSynthetic Peptide Drug Discovery and Evaluation Engineering Research Center, China Pharmaceutical University, Nanjing 211198, China.
Dong WangSynthetic Peptide Drug Discovery and Evaluation Engineering Research Center, China Pharmaceutical University, Nanjing 211198, China.
Sarra SetrerrahmaneNanjing ANJI Biotechnology Co., Ltd., Nanjing 210033, China.
Jean MartinezInstitut des Biomolécules Max Mousseron (IBMM), Université de Montpellier, CNRS, ENSCM, Pôle Chimie Balard Recherche, Montpellier cedex 5 34293, France.
Han-Mei XuSynthetic Peptide Drug Discovery and Evaluation Engineering Research Center, China Pharmaceutical University, Nanjing 211198, China.
China Pharmaceutical University · CNUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine plays a crucial role in regulating brain activity and movement and modulating human behavior, cognition and mood. Regulating dopamine signaling may improve cognitive abilities and physical functions during aging. Acein, a nonapeptide of sequence H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH is able to stimulate dopamine secretion in the brain. By using genetic editing and lifespan investigation in

Indexed as

Caenorhabditis elegans ProteinsLongevityAgedAgingAnimalsCaenorhabditis elegansDopamineHumansPeptidesCaenorhabditis elegans ProteinsDopaminePeptidesAceinagingCaenorhabditis elegansclec-126dopamine

Identifiers

PMID38154108
PMCPMC10781461
OpenAlexW4390264075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.