Evidence map›Paper›PMID 38153785›Full record

ArticleJMIR medical education2023

Differentiating ChatGPT-Generated and Human-Written Medical Texts: Quantitative Study.

Wenxiong Liao, Zhengliang Liu, Haixing Dai, Shaochen Xu, Zihao Wu, Yiyang Zhang, Xiaoke Huang, Dajiang Zhu, Hongmin Cai, Quanzheng Li and 2 more

Abstract read
In one paragraph

Article in JMIR medical education, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. A collaborative large language model for drug analysis.Nature biomedical engineering · 2026
    Article
  3. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
    Review
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  15. Review
  16. SYNFAC-EDIT: Synthetic Imitation Edit Feedback for Factual Alignment in Clinical Summarization.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2024
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenxiong LiaoSchool of Computer Science and Engineering, South China University of Technology, Guangzhou, China.ORCID 0000-0002-9432-9426
Zhengliang LiuSchool of Computing, University of Georgia, Athens, GA, United States.ORCID 0000-0001-7061-6714
Haixing DaiSchool of Computing, University of Georgia, Athens, GA, United States.ORCID 0000-0003-0409-6129
Shaochen XuSchool of Computing, University of Georgia, Athens, GA, United States.ORCID 0009-0008-0802-9218
Zihao WuSchool of Computing, University of Georgia, Athens, GA, United States.ORCID 0000-0001-7483-6570
Yiyang ZhangSchool of Computer Science and Engineering, South China University of Technology, Guangzhou, China.ORCID 0000-0001-5625-0971
Xiaoke HuangSchool of Computer Science and Engineering, South China University of Technology, Guangzhou, China.ORCID 0000-0002-1795-3065
Dajiang ZhuDepartment of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX, United States.ORCID 0000-0002-6940-3911
Hongmin CaiSchool of Computer Science and Engineering, South China University of Technology, Guangzhou, China.ORCID 0000-0002-2747-7234
Quanzheng LiDepartment of Radiology, Massachusetts General Hospital, Boston, MA, United States.ORCID 0000-0002-9651-5820
Tianming LiuSchool of Computing, University of Georgia, Athens, GA, United States.ORCID 0000-0002-8132-9048
Xiang LiDepartment of Radiology, Massachusetts General Hospital, Boston, MA, United States.ORCID 0000-0002-9851-6376

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLarge language models, such as ChatGPT, are capable of generating grammatically perfect and human-like text content, and a large number of ChatGPT-generated texts have appeared on the internet. However, medical texts, such as clinical notes and diagnoses, require rigorous validation, and erroneous medical content generated by ChatGPT could potentially lead to disinformation that poses significant harm to health care and the general public.

objectiveThis study is among the first on responsible artificial intelligence-generated content in medicine. We focus on analyzing the differences between medical texts written by human experts and those generated by ChatGPT and designing machine learning workflows to effectively detect and differentiate medical texts generated by ChatGPT.

methodsWe first constructed a suite of data sets containing medical texts written by human experts and generated by ChatGPT. We analyzed the linguistic features of these 2 types of content and uncovered differences in vocabulary, parts-of-speech, dependency, sentiment, perplexity, and other aspects. Finally, we designed and implemented machine learning methods to detect medical text generated by ChatGPT. The data and code used in this paper are published on GitHub.

resultsMedical texts written by humans were more concrete, more diverse, and typically contained more useful information, while medical texts generated by ChatGPT paid more attention to fluency and logic and usually expressed general terminologies rather than effective information specific to the context of the problem. A bidirectional encoder representations from transformers-based model effectively detected medical texts generated by ChatGPT, and the F

conclusionsAlthough text generated by ChatGPT is grammatically perfect and human-like, the linguistic characteristics of generated medical texts were different from those written by human experts. Medical text generated by ChatGPT could be effectively detected by the proposed machine learning algorithms. This study provides a pathway toward trustworthy and accountable use of large language models in medicine.

Indexed as

AlgorithmsArtificial IntelligenceDisinformationElectric Power SuppliesHealth FacilitiesHumansartificial intelligenceChatGPTlinguistic analysismachine learningmedical ethicsmedical textstext classification

Identifiers

PMID38153785
PMCPMC10784984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.