Evidence map›Paper›PMID 38153623›Full record

SynthesisBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024

Role of vulvovaginal candidiasis infection in infertility: systematic review and meta-analysis.

Ana Luiza P Córdova, Stéfani Z M Fontanella, Tamy Colonetti, Maria Laura Rodrigues Uggioni, Antonio José Grande, Maria Carolina Saggioratto, Eduardo Schmitt Testoni, Maria Inês Rosa

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Anatomopathological uterine findings ofJournal of medical microbiology · 2026
    Article
  2. Candida albicans migrates itself from the vagina to the uterus and ovaries in estrogenized mice.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. What Do the General Public Know about Infertility and Its Treatment?European journal of investigation in health, psychology and education · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ana Luiza P CórdovaGynecology and Obstetrics Medical Residency Program, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Stéfani Z M FontanellaGynecology and Obstetrics Medical Residency Program, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Tamy ColonettiLaboratory of Translational Biomedicine, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Maria Laura Rodrigues UggioniLaboratory of Translational Biomedicine, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.ORCID http://orcid.org/0000-0001-8883-287X
Antonio José GrandeLaboratory of Evidence-Based Practice, Universidade Estadual do Mato Grosso do Sul, Campo Grande, MS, Brazil.
Maria Carolina SaggiorattoLaboratory of Translational Biomedicine, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Eduardo Schmitt TestoniLaboratory of Translational Biomedicine, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Maria Inês RosaLaboratory of Translational Biomedicine, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil. mir@unesc.net.
Universidade do Extremo Sul Catarinense · BRUniversidade Estadual de Mato Grosso do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the relationship between fungal infection in the female genital tract and infertility. DATA SOURCES: A systematic review was carried out, and the search was conducted in Medline, Embase, Web of Science, Google Scholar, and Cochrane Library databases until August 2022. The search strategy used standardized keywords such as "candidiasis" and "infertility," combined with their respective synonyms. The search was limited to human studies, with no language restrictions. STUDY ELIGIBILITY CRITERIA: Primary articles that evaluated women of reproductive age with and without infertility and related to the presence or absence of candidiasis were included. STUDY APPRAISAL AND SYNTHESIS

methodsFor the analyses, the odds ratio association measure was used with a confidence interval of 95% using RevMan software (version 5.4).

resultsEight studies, published between 1995 and 2021 in different countries around the world, were included in this systematic review. Two studies were excluded after sensitivity analysis. A total of 909 participants were included in the group of infertile women and 2363 women in the control group. The age of the evaluated women varied between 18 and 50 years. The random effect model was used and showed no significant difference when comparing candidiasis between fertile and infertile women (odds ratio: 1.44; 95% confidence interval 0.86, 2.41 p= 0.17).

conclusionsThere was no association between candidiasis and female sterility.

Indexed as

Candidiasis, VulvovaginalInfertility, FemaleAdolescentAdultFemaleHumansMiddle AgedYoung AdultCandidiasisDysbiosisInfertilityVaginal infection

Identifiers

PMID38153623
PMCPMC10920545
OpenAlexW4390340669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.