ArticleClinical oral investigations2023
Decreased bone mineral density is associated with an increased number of teeth with periodontitis progression: a 5-year retrospective cohort study.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Association of mandibular cortical erosion with chronic periodontitis, apical periodontitis, and tooth fracture in Japanese women aged 40 years and older: An artificial intelligence-based analysis.Osteoporosis and sarcopenia · 2026Article
- Periodontal Disease and Osteoporosis: A Bidirectional Relationship.Advances in experimental medicine and biology · 2026Review
- Using the Canadian Longitudinal Study on Aging to examine the association between tooth loss and hip bone mineral density.Frontiers in dental medicine · 2026Article
- Review
- Epidemiology of oral health in older adults aged 65 or over: prevalence, risk factors and prevention.Aging clinical and experimental research · 2025Review
- Link between fertility behavior and edentulous jaw in middle-aged Chinese women: a cross-sectional study from the CHARLS.BMC oral health · 2025Article
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Authors and funding
6 authors.
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Abstract
objectiveLongitudinal studies on the systemic bone loss-periodontitis relationship are limited with disparate results. The aim of this study was to investigate the association between bone mineral density (BMD) and periodontitis progression, controlling for other covariables in a Thai population. MATERIALS AND
methodsIn 2,418 participants, BMD values of the lumbar spine, femoral neck, and total hip were measured with dual-energy X-ray absorptiometry at baseline. Each participant's BMD status was classified as normal, osteopenia, or osteoporosis. Full mouth periodontal examinations on 6 sites/tooth were performed at baseline and 5-year follow-up visits. Periodontitis progression was defined as a tooth presenting an additional proximal CAL loss of ≥ 3 mm or an additional lost tooth with a baseline CAL ≥ 5 mm. The risk effects of BMD status on the number of teeth with periodontitis progression were analyzed using multivariate Poisson regression.
resultsBaseline BMD status of osteoporosis was associated with an increased number of teeth with periodontitis progression in the subgroups of postmenopausal women, non-smokers, and participants with periodontitis stage III/IV with adjusted risk ratios of 1.31 (95% CI = 1.09-1.58), 1.19 (95% CI = 1.04-1.36), and 1.13 (95% CI = 1.00-1.28), respectively.
conclusionBaseline BMD in the osteoporosis range increased the risk of having a greater number of teeth with periodontitis progression in specific participant subgroups. CLINICAL RELEVANCE: Decreased BMD is a potential factor affecting periodontitis progression risk in some individuals. Multidisciplinary approaches in educating and maintaining patients' bone-oral health may help improve their quality of life.
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