Evidence map›Paper›PMID 38152668›Full record

ArticleFrontiers in public health2023

Baseline and early changes in laboratory parameters predict disease severity and fatal outcomes in COVID-19 patients.

Addisu Gize, Yerega Belete, Melkayehu Kassa, Wondewosen Tsegaye, Gadissa Bedada Hundie, Birhan Mesele Belete, Mahteme Bekele, Berhan Ababaw, Yosef Tadesse, Bereket Fantahun and 3 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Addisu GizeSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Yerega BeleteSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Melkayehu KassaSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Wondewosen TsegayeSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Gadissa Bedada HundieSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Birhan Mesele BeleteDepartment of Internal Medicine, School of Medicine, College of Health Science and Medicine, Wollo University, Dessie, Ethiopia.
Mahteme BekeleSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Berhan AbabawSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Yosef TadesseSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Bereket FantahunSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Sisay SirguSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Solomon AliSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Anteneh Mehari TizazuSchool of Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) has become the worst catastrophe of the twenty-first century and has led to the death of more than 6.9 million individuals across the globe. Despite the growing knowledge of the clinicopathological features of COVID-19, the correlation between baseline and early changes in the laboratory parameters and the clinical outcomes of patients is not entirely understood. Methods: Here, we conducted a time series cross-sectional study aimed at assessing different measured parameters and socio-demographic factors that are associated with disease severity and the outcome of the disease in 268 PCR-confirmed COVID-19 Patients. Results: We found COVID-19 patients who died had a median age of 61 years (IQR, 50 y - 70 y), which is significantly higher ( Conclusion: To conclude here, we showed that simple laboratory parameters can be used to predict severity and outcome in COVID-19 patients. As these parameters are simple, inexpensive, and radially available in most resource-limited countries, they can be extrapolated to future viral epidemics or pandemics to allocate resources to particular patients.

Indexed as

COVID-19AdultCross-Sectional StudiesHumansMiddle AgedPatient AcuitySARS-CoV-2COVID-19laboratory parametersmortalityresource-limited countriesseverity

Identifiers

PMID38152668
PMCPMC10751315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.