Evidence map›Paper›PMID 38152504›Full record

ArticleECS sensors plus2023

Perspective-Assessing Electrochemical, Aptamer-Based Sensors for Dynamic Monitoring of Cellular Signaling.

Celeste R Rousseau, Hope Kumakli, Ryan J White

Abstract read
In one paragraph

Article in ECS sensors plus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Celeste R RousseauDepartment of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, United States of America.
Hope KumakliDepartment of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, United States of America.
Ryan J WhiteDepartment of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, United States of America.ORCID https://orcid.org/0000-0003-0849-0457

Funding

Developing Electrochemical Sensors to Enable Quantitative Measure of Gliotransmitter Release from AstrocytesR01NS134365 · NINDS · UNIVERSITY OF CINCINNATI · PI Ryan J. White, Yi Xiao · 2023 to 2026
$1.5M
NINDS NIH HHS R01 NS134365
6 · The paper itself

Abstract

Electrochemical, aptamer-based (E-AB) sensors provide a generalizable strategy to quantitatively detect a variety of targets including small molecules and proteins. The key signaling attributes of E-AB sensors (sensitivity, selectivity, specificity, and reagentless and dynamic sensing ability) make them well suited to monitor dynamic processes in complex environments. A key bioanalytical challenge that could benefit from the detection capabilities of E-AB sensors is that of cell signaling, which involves the release of molecular messengers into the extracellular space. Here, we provide a perspective on why E-AB sensors are suited for this measurement, sensor requirements, and pioneering examples of cellular signaling measurements.

Indexed as

aptamercell signalingelectrochemical aptamer-based sensorselectrochemistry

Identifiers

PMID38152504
PMCPMC10750225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.