Evidence map›Paper›PMID 38152481›Full record

ArticleEuropean urology open science2023

Not Only Length Matters! Impact of the Ileal Width on the Capacity of the Orthotopic Neobladder: The AADAPT Formula Tested on the Animal Model.

Filippo Annino, Thierry Piechaud, Robert Ghattas, Richard Gaston, Anastasios D Asimakopoulos

Abstract read
In one paragraph

Article in European urology open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Filippo AnninoUnit of Urology, Azienda Toscana Sud-Est, San Donato Hospital, Arezzo, Italy.
Thierry PiechaudUnit of Urology, Clinique Saint-Augustin, Bordeaux, France.
Robert GhattasIndependent Mathematician.
Richard GastonUnit of Urology, Clinique Saint-Augustin, Bordeaux, France.
Anastasios D AsimakopoulosUnit of Urology, Fondazione PTV Policlinico Tor Vergata, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The capacity of a given shape of an orthotopic ileal neobladder (ONB) varies significantly, although the same length of preterminal ileum is utilised. Objective: To investigate the variability of the human ileal width and to create a mathematical formula that calculates its impact on the neobladder capacity. Design setting and participants: During 50 consecutive cases of robotic pelvic surgery, a segment of preterminal ileum was identified and the width was measured. A mathematical formula was created to calculate, for a given ileal length and width, the neobladder capacity and, for a given ileal width and neobladder capacity, the length of the (pre)terminal ileum to harvest. The accuracy of our model was tested on 28 pouches created by swine ileum. Outcome measurements and statistical analysis: The interindividual variability of the ileal width and its impact on the ileal neobladder capacity was investigated. Results and limitations: The mean hemicircumference of the human distal ileum is 2.43 ± 0.39 cm (range 2-3.5 cm). According to our geometric model and as confirmed in the swine model, an increase of 1 cm in ileal width increases the neobladder capacity by 85%. The Pearson correlation coefficient reported a strong positive relationship between the formula-calculated and effective volumes of the pouch ( Conclusions: The ileal width impacts the capacity of the ONB. For a given type of ONB, no standard length of ileum should be harvested; instead, the length should be tailored to the width of the ileum for a given patient. Clinical studies are required to confirm our model. Patient summary: We demonstrated the variability of the ileal width among humans, and we provided a mathematical formula tested on swine that evaluates the impact of the ileal width on the capacity of the orthotopic ileal neobladder.

Indexed as

Bladder cancerCystectomyIleumSmall intestineUrinary bladderUrinary diversion

Identifiers

PMID38152481
PMCPMC10751539

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.