Evidence map›Paper›PMID 38152405›Full record

Observational studyFrontiers in immunology2023

Clinical characteristics and prognosis in patients with neuronal surface antibody-mediated autoimmune encephalitis: a single-center cohort study in China.

Teng Huang, Fei Liu, Baojie Wang, Chunjuan Wang, Maolin Hao, Shougang Guo

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Teng HuangDepartment of Neurology, Shandong Provincial Hospital, Shandong University, Jinan, China.
Fei LiuDepartment of Neurology, Shandong Second Provincial General Hospital, Jinan, China.
Baojie WangDepartment of Neurology, Shandong Second Provincial General Hospital, Jinan, China.
Chunjuan WangDepartment of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Maolin HaoDepartment of Neurology, Shandong Second Provincial General Hospital, Jinan, China.
Shougang GuoDepartment of Neurology, Shandong Provincial Hospital, Shandong University, Jinan, China.
Shandong Provincial Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This retrospective observational study primarily aimed to analyse the clinical characteristics of patients with neuronal surface antibody-mediated autoimmune encephalitis (AE) in China and report their prognosis after immunotherapy. Methods: Clinical characteristics, laboratory or imaging examinations, and treatment outcomes of 103 patients diagnosed with AE between 1 September 2014 and 31 December 2020 were collected. Univariate and multivariate logistic regression analyses were performed to determine the predictors of poor prognosis. Results: Overall, 103 patients were enrolled in the study. The main clinical symptoms included seizures (74.8%), psychiatric and behavior disorders (66.0%), cognitive deficits (51.5%), disturbances of consciousness (45.6%), and movement disorders Conclusions: Different AE subtypes demonstrated different clinical symptom spectra throughout the disease stage. Anti-LGI1 encephalitis and anti-CASPR2 encephalitis were more sensitive to first-line and second-line treatments. Anti-GABA

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisAutoantibodiesChinaCohort StudiesHumansPrognosisAutoantibodiesautoimmune encephalitisclinical characteristicsimmunotherapyneutrophil-to-lymphocyte ratioprognosis

Identifiers

PMID38152405
PMCPMC10751914
OpenAlexW4389622348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.