ArticleFrontiers in endocrinology2023
Association between serum total bilirubin and diabetic kidney disease in US diabetic patients.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Association between total bilirubin levels and the risk of acute kidney injury: a large hospital- based cohort study.BMC nephrology · 2026Article
- Association of Serum Total Bilirubin to Cholesterol Ratio With Progression of Chronic Kidney Disease in Patients With Type 2 Diabetes: A Retrospective Cohort Study.Journal of diabetes · 2025Article
- A cross-sectional observational study of the association between biochemistry profiles and the risk of age-related macular degeneration.Scientific reports · 2025Observational
- The Correlation Between Plasma Bilirubin Concentrations and Glomerular Filtration Rate and Creatinine in Type 2 Diabetes with Renal Damage.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- Association between physiological serum total bilirubin concentrations and the progression of diabetic nephropathy.Frontiers in endocrinology · 2025Article
- Association between serum total bilirubin with Parkinson's disease among American adults (NHANES 1999 to 2018).Heliyon · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bilirubin has been widely reported to be a protective factor against diabetic kidney disease (DKD) in Asian populations. However, few large-sample analyses have been conducted in American populations. This study aimed to investigate the association between serum total bilirubin (STB) level and DKD in a US diabetic cohort. Methods: This cross-sectional study enrolled participants from the National Health and Nutrition Examination Survey (NHANES) 2003-2018. Univariate and multivariate logistic regression analyses were performed to assess the association between STB level and DKD. Three models were conducted to control the potential confounding factors. Subgroup analysis was carried out for further validation. Results: Among the 5,355 participants, the median age [interquartile range (IQR)] was 62 [52-71] years; 2,836 (52.96%) were male, and 1,576 (29.43%) were diagnosed with DKD. In the entire cohort, no significant association between STB level and DKD was observed in any logistic regression models ( Conclusion: The association of STB level with DKD may depict differences across diverse populations, among which the impact of race, sex, and age requires thorough consideration and relevant inferences should be interpreted cautiously.
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