Evidence map›Paper›PMID 38151901›Full record

ArticleCancer medicine2024

Patient perspectives on factors influencing active surveillance adherence for low-risk prostate cancer: A qualitative study.

Lalita Subramanian, Sarah T Hawley, Ted A Skolarus, Aaron Rankin, Michael D Fetters, Karla Witzke, Jason Chen, Archana Radhakrishnan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Overdiagnosis and Overtreatment in Prostate Cancer.Diseases (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lalita SubramanianDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Sarah T HawleyDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Ted A SkolarusCenter for Clinical Management Research, Health Services Research & Development, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
Aaron RankinDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Michael D FettersDepartment of Family Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Karla WitzkeDepartment of Urology, MyMichigan Health, Midland, Michigan, USA.
Jason ChenDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-0988-766X
Archana RadhakrishnanDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-7689-6390

Funding

De-implementation of low value castration for men with prostate cancerR37CA222885 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SAINI, SAMEER DEV, SKOLARUS, TED ALBERT · 2018 to 2023
$3.6M
Engaging PCPs to optimize active surveillance of low-risk prostate cancerK08CA245237 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RADHAKRISHNAN, ARCHANA · 2019 to 2023
$1.2M
NCI NIH HHS K08 CA245237NCI NIH HHS R37 CA222885
6 · The paper itself

Abstract

backgroundProstate cancer is the most common cancer among men in the United States. Treatment guidelines recommend active surveillance for low-risk prostate cancer, which involves monitoring for progression, to avoid or delay definitive treatments and their side effects. Despite increased uptake, adherence to surveillance remains a challenge.

methodsWe conducted semi-structured, qualitative, virtual interviews based on the Theoretical Domains Framework (TDF), with men (15) who were or had been on active surveillance for their low-risk prostate cancer in 2020. Interviews were transcribed and coded under TDF's behavioral theory-based domains. We analyzed domains related to adherence to surveillance using constructivist grounded theory to identify themes influencing decision processes in adherence.

resultsThe TDF domains of emotion, beliefs about consequences, environmental context and resources, and social influences were most relevant to surveillance adherence-. From these four TDF domains, three themes emerged as underlying decision processes: trust in surveillance as treatment, quality of life, and experiences of self and others. Positive perceptions of these three themes supported adherence while negative perceptions contributed to non-adherence (i.e., not receiving follow-up or stopping surveillance). The relationship between the TDF domains and themes provided a theoretical process describing factors impacting active surveillance adherence for men with low-risk prostate cancer.

conclusionsMen identified key factors impacting active surveillance adherence that provide opportunities for clinical implementation and practice improvement. Future efforts should focus on multi-level interventions that foster trust in surveillance as treatment, emphasize quality of life benefits and enhance patients' interpersonal experiences while on surveillance to optimize adherence.

Indexed as

Prostatic NeoplasmsQualitative ResearchWatchful WaitingAgedDecision MakingHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPatient ComplianceQuality of Lifeactive surveillanceprimary care physiciansprostate cancerquality of lifetrusturologists

Identifiers

PMID38151901
PMCPMC10807559

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.