Evidence map›Paper›PMID 38151700›Full record

ArticleImmunologic research2024

Conventional Tregs in treatment-naïve rheumatoid arthritis are deficient in suppressive function with an increase in percentage of CXCR3 and CCR6 expressing Tregs.

Vallayyachari Kommoju, Christina Mary Mariaselvam, Sree Nethra Bulusu, Chengappa Kavadichanda Ganapathy, Prakash Babu Narasimhan, Molly Mary Thabah, Vir Singh Negi

Abstract read
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In one paragraph

Article in Immunologic research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. The alterations in the gut microbiota andFrontiers in immunology · 2026
    Article
  3. Review
  4. Article
  5. The 'TNature reviews. Rheumatology · 2025
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vallayyachari KommojuDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0002-2127-1585
Christina Mary MariaselvamDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0001-8248-3920
Sree Nethra BulusuDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0001-9261-0479
Chengappa Kavadichanda GanapathyDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0002-3643-3989
Prakash Babu NarasimhanDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0001-7111-7124
Molly Mary ThabahDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India.ORCID 0000-0002-0999-7463
Vir Singh NegiDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India. vsnegi22@yahoo.co.in.ORCID 0000-0003-1518-6031
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

DST-SERB and JIPMER JIP/Res/Intra-PhD/01/2014-15DST-SERB and JIPMER SERB/F/0253/2016-17
6 · The paper itself

Abstract

In rheumatoid arthritis (RA), immune homeostasis is maintained by T regulatory cells (Tregs) that in an inflammatory milieu can change towards T-helper-like phenotypes (Th-like Tregs). Our aim was to examine the phenotypic and functional characteristics of CD4

Indexed as

Arthritis, RheumatoidReceptors, CCR6Receptors, CXCR3T-Lymphocytes, RegulatoryAdultAgedCytokinesFemaleForkhead Transcription FactorsHumansMaleMiddle AgedOsteoarthritisSynovial FluidTh17 CellsT-Lymphocyte SubsetsCCR6 protein, humanCXCR3 protein, humanCytokinesForkhead Transcription FactorsReceptors, CCR6Receptors, CXCR3CytokinesFlow cytometryRheumatoid arthritisTh17-like TregsTh1-like TregsT regulatory cells (Tregs)

Identifiers

PMID38151700
OpenAlexW4390264290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.