Evidence map›Paper›PMID 38151656›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2024

Extracellular Vesicles: the Next Frontier in Pregnancy Research.

Ali Afzal, Madeeha Khan, Zaman Gul, Rameen Asif, Sara Shahzaman, Asia Parveen, Muhammad Imran, Muhammad Babar Khawar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Ali Afzal *Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.ORCID 0000-0003-3679-1257
Madeeha Khan *College of Allied Health Sciences, Akhtar Saeed Medical and Dental College, Lahore, Pakistan.
Zaman Gul *Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Rameen Asif *Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
Sara ShahzamanMolecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
Asia ParveenDepartment of Zoology, Government College University, Lahore, Pakistan.
Muhammad ImranCenter for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan.
Muhammad Babar KhawarInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. babar.khawar@uon.edu.pk.ORCID 0000-0002-1812-0591
University of Central Punjab · PKUniversity of the Punjab · PKGovernment College University, Lahore · PKKarachi Medical and Dental College · PKShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vehicles (EVs) have been involved in several aspects of pregnancy, including endometrial receptivity, embryo implantation, and embryo-maternal communication showing them associated with pregnancy disorders, such as preeclampsia, gestational diabetes mellitus, and preterm birth. Further research is warranted to fully comprehend the exact pathophysiological roles of EVs and to develop new therapies targeting EVs thereby improving pregnancy outcomes. Herein, we review the recent knowledge on the multifaceted roles of EVs during pregnancy and address the majority of the molecular interactions between EVs, maternal, and fetal cells with an emphasis on disorders of pregnancy under the influence of EVs. Moreover, we also discuss its applications in clinical trials followed by prospects.

Indexed as

Extracellular VesiclesAnimalsEmbryo ImplantationFemaleHumansPregnancyPregnancy ComplicationsExtracellular vesiclesGestational diabetes mellitusPreeclampsiaPregnancyPreterm labor

Identifiers

PMID38151656
OpenAlexW4390263828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.