Evidence map›Paper›PMID 38150580›Full record

ArticleJournal of applied clinical medical physics2024

Development and validation of the low-cost pregnant female physical phantom for fetal dosimetry in MV photon radiotherapy.

Vjekoslav Kopačin, Hrvoje Brkić, Ana Ivković, Mladen Kasabašić, Željka Knežević, Marija Majer, Marijana Nodilo, Tajana Turk, Dario Faj

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vjekoslav KopačinFaculty of Medicine, Department of Radiology, J. J. Strossmayer University Osijek, University Hospital Center Osijek, Department of Diagnostic and Interventional Radiology, Osijek, Croatia.ORCID https://orcid.org/0000-0002-3854-6602
Hrvoje BrkićFaculty of Medicine, Department of Biophysics and Medical Physics, J. J. Strossmayer University Osijek, Osijek, Croatia.ORCID https://orcid.org/0000-0001-6692-6875
Ana IvkovićFaculty of Medicine, Department of Biophysics and Medical Physics, J. J. Strossmayer University Osijek, University Hospital Center Osijek, Department of Medical Physics, Osijek, Croatia.
Mladen KasabašićFaculty of Medicine, Department of Biophysics and Medical Physics, J. J. Strossmayer University Osijek, University Hospital Center Osijek, Department of Medical Physics, Osijek, Croatia.
Željka KneževićDivision of Materials Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Marija MajerDivision of Materials Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Marijana NodiloDivision of Materials Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Tajana TurkFaculty of Medicine, Department of Radiology, J. J. Strossmayer University Osijek, University Hospital Center Osijek, Department of Diagnostic and Interventional Radiology, Osijek, Croatia.
Dario FajFaculty of Medicine, Department of Biophysics and Medical Physics, J. J. Strossmayer University Osijek, Osijek, Croatia.ORCID https://orcid.org/0000-0002-4111-5459

Funding

Faculty of dental medicine and health Institutional project IP3-2022Faculty of medicine Institutional project IP 2023-4
6 · The paper itself

Abstract

backgroundMonte Carlo (MC) simulations or measurements in anthropomorphic phantoms are recommended for estimating fetal dose in pregnant patients in radiotherapy. Among the many existing phantoms, there is no commercially available physical phantom representing the entire pregnant woman. PURPOSE: In this study, the development of a low-cost, physical pregnant female phantom was demonstrated using commercially available materials. This phantom is based on the previously published computational phantom.

methodsThree tissue substitution materials (soft tissue, lung and bone tissue substitution) were developed. To verify Tena's substitution tissue materials, their radiation properties were assessed and compared to ICRP and ICRU materials using MC simulations in MV radiotherapy beams. Validation of the physical phantom was performed by comparing fetal doses obtained by measurements in the phantom with fetal doses obtained by MC simulations in computational phantom, during an MV photon breast radiotherapy treatment.

resultsMaterials used for building Tena phantom are matched to ICRU materials using physical density, radiation absorption properties and effective atomic number. MC simulations showed that percentage depth doses of Tena and ICRU material comply within 5% for soft and lung tissue, up to 25 cm depth. In the bone tissue, the discrepancy is higher, but again within 5% up to the depth of 5 cm. When the phantom was used for fetal dose measurements in MV photon breast radiotherapy, measured fetal doses complied with fetal doses calculated using MC simulation within 15%.

conclusionsPhysical anthropomorphic phantom of pregnant patient can be manufactured using commercial materials and with low expenses. The files needed for 3D printing are now freely available. This enables further studies and comparison of numerical and physical experiments in diagnostic radiology or radiotherapy.

Indexed as

Pregnant PeopleRadiometryComputer SimulationFemaleHumansMonte Carlo MethodPhantoms, ImagingPhotonsPregnancyRadiotherapy DosageRadiotherapy Planning, Computer-Assistedbreast neoplasmfetusmegavolt radiotherapyphantomphysicalpregnantradiation dosimetrywoman

Identifiers

PMID38150580
PMCPMC10860449

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.