ArticleMedical physics2024
Evaluation of the MRI compatibility of PET detectors modules for organ-specific inserts in a 3T and 7T MRI scanner.
Article in Medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 2 citations in OpenAlex.
- Performance of detector modules designed for the NeuroSphere brain PET system.Medical physics · 2026Article
- Impact of DOI Capability on Detector Performance: A Comparative Study of DOI and Non-DOI Detectors for High-Resolution and Sensitivity Organ-Specific PET Inserts.IEEE transactions on radiation and plasma medical sciences · 2026Article
- Comparison of Magnetic Resonance Spectra Acquired With Hybrid PET/MR and Standalone MR Scanners.Journal of magnetic resonance imaging : JMRI · 2025Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSimultaneous positron emission tomography (PET)/magnetic resonance imaging (MRI) scanners and inserts are valuable tools for accurate diagnosis, treatment planning, and monitoring due to their complementary information. However, the integration of a PET system into an MRI scanner presents technical challenges for a distortion-free operation. PURPOSE: We aim to develop a PET insert dedicated to breast imaging in combination with the 3T PET/MRI scanner Biograph mMR (Siemens Healthineers) as well as a brain PET insert for the 7T MRI scanner MAGNETOM Terra (Siemens Healthineers). For this development, we selected as a basis the C13500 series PET modules (Hamamatsu Photonics K.K.) as they offer an all-in-one solution with a scalable, modular design for compact integration with state-of-the-art performance. The original PET modules were not designed to be operated with an MRI scanner, therefore we implemented several modifications such as signal transmission via plastic optical fiber, radio frequency (RF) shielding of the front-end electronics, and filter for the power supply lines. In this work, we evaluated the mutual MRI compatibility between the modified PET modules and the 3T and 7T MRI scanner.
methodsWe used a proof-of-concept setup with two detectors to comprehensively evaluate a potential distortion of the performance of the modified PET modules whilst exposing them to a variety of MR sequences up to the peak operation conditions of the Biograph mMR. A method using the periodicity of the sequences to identify distortions of the PET events in the phase of RF pulse transmission was introduced. Vice versa, the potential distortion of the Biograph mMR was evaluated by vendor proprietary MRI compatibility test sequences. Afterwards, these studies were extended to the MAGNETOM Terra.
resultsNo distortions were introduced by gradient field switching (field strength up to 20 mT/m at a slew rate of 66.0 T/ms
conclusionOur study demonstrates the feasibility of using a modified version of the PET modules in combination with 3T and 7T MRI scanners. Building upon the encouraging MRI compatibility results from our proof-of-concept detectors, we will proceed to develop PET inserts for breast and brain imaging using these modules.
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