Evidence map›Paper›PMID 38150359›Full record

ArticleThe Gerontologist2024

Difference-Making Pathways to Frailty Through Social Factors: A Configurational Analysis.

Chava Pollak, Joe Verghese, Helena M Blumen

Open access · bronzeAbstract read
In one paragraph

Article in The Gerontologist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chava PollakDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-5102-5940
Joe VergheseDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0003-4252-2547
Helena M BlumenDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-0275-6616
Albert Einstein College of Medicine · US

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementiaR01AG062659 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BLUMEN, HELENA M · 2020 to 2024
$3.8M
Biological and neural mechanisms of fallsR01AG044007 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERGHESE, JOE · 2013 to 2017
$3.5M
Central Control of Mobility in AgingR01AG036921 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HOLTZER, ROEE · 2011 to 2015
$3.3M
CTSA K12 Program at Einstein-MontefioreK12TR004411 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Deepa Rastogi · 2023 to 2026
$3.0M
Institutional Career Development CoreKL2TR002558 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI MARANTZ, PAUL R · 2018 to 2022
$2.7M
NCATS NIH HHS K12 TR004411NCATS NIH HHS KL2 TR002558NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG036921NIA NIH HHS R01 AG044007NIA NIH HHS R01 AG062659NIA NIH HHS R01AG062659-01A1
6 · The paper itself

Abstract

BACKGROUND AND

objectivesSocial disconnection is highly prevalent in older adults and is associated with frailty. It is unclear which aspects of social disconnection are most associated with frailty, which ones are difference-making, and which combination of social factors are directly linked to frailty. RESEARCH DESIGN AND

methodsWe conducted a secondary coincidence analysis (CNA) of 1,071 older adults from the Rush Memory and Aging Project (mean age 79.3 ± 7.1; 75.8% female) to identify combinations of social factors that are difference-making for frailty. We included 7 demographic (e.g., age, sex, socioeconomic status) and structural (e.g., social network), functional (e.g., social support, social activity), and quality (e.g., loneliness) aspects of social connection. An established cut score of 0.2 on a frailty index was used to define frailty as the outcome.

resultsCNA produced 46 solution models for the presence of frailty in the data set. The top-scoring model was underfit, leaving a final complex solution path for frailty with the highest fit-robustness score that met the fit parameter cutoffs. We found that the combination of loneliness, low social activity, and older age was present 82% of the time when frailty was present. DISCUSSION AND IMPLICATIONS: The combination of loneliness, social activity, and old age is difference-making for frailty, and supports the inclusion of social factors in frailty prevention and intervention. Further research is needed in diverse data sets to better understand the interrelationships between the 3 aspects of social connection and frailty.

Indexed as

Frail ElderlyFrailtyLonelinessSocial SupportAgedAged, 80 and overAgingFemaleHumansMaleSocial FactorsSocial IsolationConfigurational comparative methodsPhysical functionSocial relationships

Identifiers

PMID38150359
PMCPMC11102007
OpenAlexW4390260513

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.