Evidence map›Paper›PMID 38149950›Full record

ReviewThe Journal of investigative dermatology2024

Role of Antigenic Stimulation in Cutaneous T-Cell Lymphomas.

Megan E Gumina, Madeline J Hooper, Xiaolong A Zhou, Sergei B Koralov

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of investigative dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Incidence trends of primary cutaneous B- and T-cell lymphoma before and after the COVID-19 pandemic.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Megan E GuminaDepartment of Pathology, Grossman School of Medicine, New York University, New York, New York, USA.
Madeline J HooperDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Xiaolong A ZhouDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address: alan.zhou@northwestern.edu.
Sergei B KoralovDepartment of Pathology, Grossman School of Medicine, New York University, New York, New York, USA. Electronic address: sergei.koralov@nyulangone.org.
New York University · USNorthwestern University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1M
Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
Microbial triggers and molecular mechanisms of Th17 mediated airway inflammation-Resubmission-1R01HL125816 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KORALOV, SERGEI BORISOVICH · 2015 to 2019
$3.3M
Role of S.aureus in Cutaneous T Cell Lymphoma PathogenesisR01CA271245 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Sergei Borisovich Koralov · 2022 to 2026
$2.7M
NCATS NIH HHS KL2 TR001424NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA271245NHLBI NIH HHS R01 HL125816
6 · The paper itself

Abstract

Cutaneous T-cell lymphoma (CTCL) involves a clonal expansion of malignant cells accumulating in the skin, a primary barrier site. CTCL has long been hypothesized to be caused or perpetuated by chronic antigen stimulation due to unknown exposures. These antigenic triggers, defined as any element that may cause activation of malignant T cells through TCR signaling, have been hypothesized to range from chemicals to microbes. This review covers current evidence supporting chemical and microbial stimuli that may act as antigenic triggers of CTCL and summarizes novel areas of investigation, in which the potential antigenicity of the exposure is still unknown.

Indexed as

Lymphoma, T-Cell, CutaneousSkin NeoplasmsHumansSkinCutaneous T-Cell LymphomaImmunologyMicrobiome

Identifiers

PMID38149950
PMCPMC10960716
OpenAlexW4390238519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.