Evidence map›Paper›PMID 38149842›Full record

ArticleeLife2023

Efficient estimation for large-scale linkage disequilibrium patterns of the human genome.

Xin Huang, Tian-Neng Zhu, Ying-Chao Liu, Guo-An Qi, Jian-Nan Zhang, Guo-Bo Chen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Xin Huang *Institute of Bioinformatics, Zhejiang University, Hangzhou, China.
Tian-Neng Zhu *Institute of Bioinformatics, Zhejiang University, Hangzhou, China.ORCID 0009-0007-7507-4521
Ying-Chao LiuInstitute of Bioinformatics, Zhejiang University, Hangzhou, China.
Guo-An QiInstitute of Bioinformatics, Zhejiang University, Hangzhou, China.ORCID 0000-0002-2412-3932
Jian-Nan ZhangAlibaba Group, Hangzhou, China.
Guo-Bo ChenCenter for General Practice Medicine, Department of General Practice Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.ORCID 0000-0001-5475-8237
Institute of Bioinformatics · INZhejiang Provincial People's Hospital · CNAlibaba Group (United States) · US

Funding

China National Tobacco Corporation 110202101032(JY-09)National Natural Science Foundation of China 31771392
6 · The paper itself

Abstract

In this study, we proposed an efficient algorithm (X-LD) for estimating linkage disequilibrium (LD) patterns for a genomic grid, which can be of inter-chromosomal scale or of small segments. Compared with conventional methods, the proposed method was significantly faster, dropped from

Indexed as

Genome, HumanPolymorphism, Single NucleotideAlgorithmsGenomicsHumansLinkage Disequilibriumefficient algorithmevolutionary biologygeneticsgenomicshumaninter-chromosomelinkage disequilibrium pattern

Identifiers

PMID38149842
PMCPMC10752592
OpenAlexW4387379034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.