Evidence map›Paper›PMID 38149773›Full record

ReviewNeurourology and urodynamics2024

Is the time right for a new initiative in mathematical modeling of the lower urinary tract? ICI-RS 2023.

Margot S Damaser, Françoise A Valentini, Francesco Clavica, Ilias Giarenis

Abstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margot S DamaserDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-4743-9283
Françoise A ValentiniPhysical Medicine and Rehabilitation Department, Rothschild Hospital, Sorbonne Université, Paris, France.ORCID http://orcid.org/0000-0002-8639-4631
Francesco ClavicaARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-8967-5877
Ilias GiarenisDepartment of UroGynaecology, Norfolk and Norwich University Hospital, Norwich, UK.ORCID http://orcid.org/0000-0002-7644-9010

Funding

RR&D Research Career Scientist Award Application - Renewal of Margot Damaser SRCS AwardIK6RX003843 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI MARGOT S. DAMASER · 2022 to 2026
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RRD VA IK6 RX003843
6 · The paper itself

Abstract

introductionA session at the 2023 International Consultation on Incontinence - Research Society (ICI-RS) held in Bristol, UK, focused on the question: Is the time right for a new initiative in mathematical modeling of the lower urinary tract (LUT)? The LUT is a complex system, comprising various synergetic components (i.e., bladder, urethra, neural control), each with its own dynamic functioning and high interindividual variability. This has led to a variety of different types of models for different purposes, each with advantages and disadvantages.

methodsWhen addressing the LUT, the modeling approach should be selected and sized according to the specific purpose, the targeted level of detail, and the available computational resources. Four areas were selected as examples to discuss: utility of nomograms in clinical use, value of fluid mechanical modeling, applications of models to simplify urodynamics, and utility of statistical models.

resultsA brief literature review is provided along with discussion of the merits of different types of models for different applications. Remaining research questions are provided.

conclusionsInadequacies in current (outdated) models of the LUT as well as recent advances in computing power (e.g., quantum computing) and methods (e.g., artificial intelligence/machine learning), would dictate that the answer is an emphatic "Yes, the time is right for a new initiative in mathematical modeling of the LUT."

Indexed as

UrodynamicsHumansLower Urinary Tract SymptomsModels, BiologicalModels, TheoreticalNomogramsUrethraUrinary Bladderbladdermathematical modelingmechanical modelingnomogramstatistical modelingurethraurodynamics

Identifiers

PMID38149773
PMCPMC11610278

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.