Evidence map›Paper›PMID 38149766›Full record

ReviewPharmacology research & perspectives2024

Human organ chips for regenerative pharmacology.

Girija Goyal, Chaitra Belgur, Donald E Ingber

Abstract readReview
In one paragraph

Review in Pharmacology research & perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Human organ chips for regenerative pharmacology.Pharmacology research & perspectives · 2024
    Review
  6. Progress and application of lung-on-a-chip for lung cancer.Frontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Girija GoyalWyss Institute for Biologically, Inspired Engineering at Harvard University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2163-2205
Chaitra BelgurWyss Institute for Biologically, Inspired Engineering at Harvard University, Boston, Massachusetts, USA.
Donald E IngberWyss Institute for Biologically, Inspired Engineering at Harvard University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4319-6520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human organs-on-chips (organ chips) are small microfluidic devices that allow human cells to perform complex organ-level functions in vitro by recreating multi-cellular and multi-tissue structures and applying in vivo-like biomechanical cues. Human Organ Chips are being used for drug discovery and toxicology testing as an alternative to animal models which are ethically challenging and often do not predict clinical efficacy or toxicity. In this mini-review, we summarize our presentation that reviewed the state of the art relating to these microfluidic culture devices designed to mimic specific human organ structures and functions, and the application of Organ Chips to regenerative pharmacology.

Indexed as

Lab-On-A-Chip DevicesMicrophysiological SystemsAnimalsDrug DiscoveryHumansModels, Animalclinical predictivityintestine-on-a-chiplung-on-a-chiplymph Node-on-a-chipmicrophysiological systemsorgans on chips

Identifiers

PMID38149766
PMCPMC10751726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.