Evidence map›Paper›PMID 38149208›Full record

ArticleHeliyon2023

General joint hypermobility in temporomandibular joint disease; clinical characteristics, biomarkers, and surgical aspects.

Mattias Ulmner, Rachael Sugars, Aron Naimi-Akbar, Janne Elin Reseland, Bodil Lund

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mattias UlmnerMedical Unit of Plastic Surgery and Oral and Maxillofacial Surgery, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Rachael SugarsDepartment of Dental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Aron Naimi-AkbarHealth Technology Assessment-Odontology, Malmö University, 205 06, Malmö, Sweden.
Janne Elin ReselandDepartment of Biomaterials, Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, 0317, Oslo, Norway.
Bodil LundMedical Unit of Plastic Surgery and Oral and Maxillofacial Surgery, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SEMalmö University · SEUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed at identifying biomarkers in the temporomandibular joint (TMJ) synovial tissue analysing 28 extra cellular matrix proteins in TMJ diseased patients, classified with either general joint hypermobility (GJH) or normal joint mobility (NJM), and to compile clinical and protein characterisation to reveal potential surgical predictive factors. Study design: A prospective observational cohort study including 97 consecutive patients scheduled for TMJ surgery was performed. Joint mobility and several other predefined clinical variables were recorded. Synovial tissue was harvested during surgery followed by examination using multi-analytic profiling. A multivariate quantile regression model was used for analysis purposes. Results: The GJH/NJM ratio was 2:5. The GJH cohort were younger ( Conclusions: GJH was more common in the study cohort compared to general population frequencies, but GJH was not a negative factor for surgical outcome. Young age and female gender correlated to GJH. No TMJ biomarkers were GJH specific, and the results suggested that TMJ diagnosis more strongly correlated to the protein profile compared to GJH and the other investigated variables.

Indexed as

ArthroscopyExtracellular matrix proteinsJoint diseasesProteinsSynovial membraneTemporomandibular jointTemporomandibular joint disorders

Identifiers

PMID38149208
PMCPMC10750043
OpenAlexW4389166147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.