ArticleNature photonics2023
Optical-resolution photoacoustic microscopy with a needle-shaped beam.
Article in Nature photonics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed, 133 citations in OpenAlex.
- Parallel multilayer photoacoustic microscopy of slide-free histology using a droplet-shaped UV beam.Science advances · 2026Article
- Label-free ultraviolet photoacoustic microscopy for multiscale structural phenotyping of epithelial morphogenesis in organoid-derived intestinal epithelial wrinkle tissue.Photoacoustics · 2026Article
- Electrically switchable dual-focus metalens for depth-extended in vivo photoacoustic imaging of ophthalmic vascular disease.Light, science & applications · 2026Article
- A Label-Free Ultraviolet Photoacoustic Microscopy Enables Nuclear Imaging and Toxicity Assessment in an Intact Brain Organoid.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Ultra-sensitive wideband diffraction-grating-coupled-mode Fabry-Pérot resonators for ultrasound and photoacoustic detection.Photoacoustics · 2026Article
- Volumetric FLASH dosimetryPhysics in medicine and biology · 2026Article
- Double-pulse laser capture microdissection with a needle beam for reduced collateral damage in biological samples.Biomedical optics express · 2026Article
- Three-dimensional aperture-driven photoacoustic tomography (3D-ADPAT).Science advances · 2026Article
- Tracer Techniques in Ophthalmology: Ocular Applications and Systemic Connections.Diagnostics (Basel, Switzerland) · 2026Review
- Multifocal Optical-Resolution Photoacoustic Microscopy With a Masked Single-Element Transducer.IEEE transactions on medical imaging · 2026Article
- Fully integrated photoacoustic microscopy for multi-scale and longitudinal imaging in translational biomedical applications.Biomedical optics express · 2026Article
- Deep computational photoacoustic mesoscopy through heterogeneous tissues enabled by scanning compensation and angular-spectrum enhancement.Photoacoustics · 2026Article
- Super-resolution functional photoacoustic microscopy via label-free cell tracking.Light, science & applications · 2026Article
- A Comparative Study on Signal Decomposition Techniques for Stimulated Raman Photoacoustic Microscopy.Journal of biophotonics · 2026Article
- Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- An electrophilicity-engineered magnetic sensor for MRI detection of dormant tumor cell clusters.Science advances · 2026Article
- Label-free mid-infrared dichroism-sensitive photoacoustic microscopy for histostructural analysis of engineered heart tissues.Light, science & applications · 2026Article
- Needle beam two-photon microscopy for simultaneous multiplane neural and vascular imaging in awake mice.PhotoniX · 2026Article
- A handheld photoacoustic microscopic probe integrating a transparent ultrasound transducer and a fiber scanner.Nature communications · 2025Article
- Reconstructing Focal Topological Curves through Vortex Spots from Multifocal Metasurfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
Optical-resolution photoacoustic microscopy (OR-PAM) can visualize wavelength-dependent optical absorption at the cellular level. However, OR-PAM suffers from a limited depth of field (DOF) due to the tight focus of the optical excitation beam, making it challenging to acquire high-resolution images of samples with uneven surfaces or high-quality volumetric images without z-scanning. To overcome this limitation, we propose needle-shaped beam photoacoustic microscopy (NB-PAM), which can extend the DOF to up to ~28-fold Rayleigh lengths via customized diffractive optical elements (DOEs). The DOE generate a needle beam with a well-maintained beam diameter, a uniform axial intensity distribution, and negligible sidelobes. The advantage of using NB-PAM is demonstrated by both histology-like imaging of fresh slide-free organs using a 266 nm laser and in vivo mouse brain vasculature imaging using a 532 nm laser. The approach provides new perspectives for slide-free intraoperative pathological imaging and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.