Evidence map›Paper›PMID 38148931›Full record

ReviewAmerican journal of clinical and experimental urology2023

The use of beta-sitosterol for the treatment of prostate cancer and benign prostatic hyperplasia.

Jill A Macoska

Open access · greenAbstract readReview
In one paragraph

Review in American journal of clinical and experimental urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Phytochemical Profiling and Antioxidant Activity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Pine-Extracted Phytosterol β-Sitosterol (APOPROSTATPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Extraction of Seed Oil fromFoods (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jill A MacoskaCenter for Personalized Cancer Therapy, The University of Massachusetts Boston Boston, MA, USA.
Boston University · US

Funding

Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI MACOSKA, JILL A., MARKER, PAUL C · 2014 to 2023
$12.8M
NIDDK NIH HHS U54 DK104310
6 · The paper itself

Abstract

Herbal supplements are widely used to enhance prostate health. These supplements may contain several types of plant sterols, vitamins, and minerals. By weight, however, plant sterols make up an abundant ingredient component, with saw palmetto extract or its primary component, beta-sitosterol, often comprising the most abundant sterol. Saw palmetto extract/beta-sitosterol has been shown to promote anti-tumorigenic processes in prostate cancer cells and rodent models of prostate cancer. It has also been shown to inhibit the 5α-reductase enzyme, thereby behaving similarly to finasteride and dutasteride, which are widely used to treat prostatic enlargement, or benign prostatic hyperplasia (BPH). The aim of this study is to critically examine

Indexed as

aza-steroidbenign prostatic hyperplasiaBeta-sitosterolcollagenherbal supplementphytosterolprostate cancersaw palmetto

Identifiers

PMID38148931
PMCPMC10749388
OpenAlexW4390280169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.