Evidence map›Paper›PMID 38148438›Full record

ArticleInternational journal of computer assisted radiology and surgery2024

A novel pneumatic drill for bone biopsy under MRI imaging.

Elizabeth Fischer, Mikias Gebremeskel, Dan Stoianovici, Karun Sharma, Kevin Cleary

Abstract read
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In one paragraph

Article in International journal of computer assisted radiology and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elizabeth FischerSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA. emfischer2@childrensnational.org.ORCID http://orcid.org/0000-0001-5967-3072
Mikias GebremeskelSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Dan StoianoviciBrady Urological Institute, Johns Hopkins Medicine, Baltimore, MD, USA.
Karun SharmaSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Kevin ClearySheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Children's National · USJohns Hopkins University · US

Funding

Pneumatic Drill and Robot for MRI-Guided Pediatrics Long Bone BiopsyR01CA248191 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI CLEARY, KEVIN R., SHARMA, KARUN V · 2020 to 2023
$2.3M
NCI NIH HHS 5R01CA248191-03
6 · The paper itself

Abstract

purposeBone biopsies are currently conducted under computed tomography (CT) guidance using a battery-powered drill to obtain tissue samples for diagnosis of suspicious bone lesions. However, this procedure is suboptimal as images produced under CT lack soft tissue discrimination and involve ionizing radiation. Therefore, our team developed an MRI-safe pneumatic drill to translate this clinical workflow into the MR environment, which can improve target visualization and eliminate radiation exposure. We compare drill times and quality of samples between the 2 drills using animal bones.

methodsFive porcine spare rib bones were obtained from a butcher shop. Each bone was drilled twice using the Arrow OnControl battery-powered drill and twice using our pneumatically actuated drill. For this study, we used an 11-gauge bone biopsy needle set with an internal core capturing thread. A stopwatch recorded the overall time of drilling for each specimen obtained.

resultsAll 20 samples collected contained a high-quality inner core and cortex. The total average time for drilling with the pneumatic drill was 8.5 s (+ / - 2.5 s) and 7.1 s (+ / - 1.4 s) with the standard battery-powered drill.

conclusionBoth drills worked well and were able to obtain comparable specimens. The pneumatic drill took slightly longer, 1.39 s on average, but this extra time would not be significant in clinical practice. We plan to use the pneumatic drill to enable MRI-safe bone biopsy for musculoskeletal lesions. Biopsy under MRI would provide excellent lesion visualization with no ionizing radiation.

Indexed as

Bone and BonesBone DiseasesBiopsyHumansMagnetic Resonance ImagingTomography, X-Ray ComputedBattery-powered drillBone biopsyInterventional MRIPneumatically powered drill

Identifiers

PMID38148438
OpenAlexW4390225952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.