SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024
Influence of instrumentation type on outcomes after surgical management of spondylodiscitis: a systematic review and meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Outcomes of 3D-printed titanium cages for surgical reconstruction in infectious spondylodiscitis: a systematic review.Journal of spine surgery (Hong Kong) · 2026Review
- Exploratory Analysis of Factors Affecting 30-Day, 90-Day, and 1-Year Readmission After Surgical Treatment of Primary Spinal Infection in Adults.Journal of clinical medicine · 2026Article
- Prediction and risk factors for one year mortality in patients after surgery for pyogenic spondylodiscitis.Neurosurgical review · 2026Article
- Clinical characteristics, microbiological landscape, and severity-stratified management of pyogenic spondylitis: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Observational
- Risk factors for revision surgery due to construct failure after instrumented treatment of pyogenic spondylodiscitis.Brain & spine · 2026Article
- Cervical Pyogenic Spondylitis: A Comprehensive Review of Diagnosis and Treatment Strategy.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSpondylodiscitis refers to infection of the intervertebral disk and neighboring structures. Outcomes based on instrumentation type are not well reported in the literature, but are important in establishing guidelines for surgical management of spondylodiscitis. This study aims to clarify the effect of instrumentation material selection on clinical and radiographic outcomes in patients with spondylodiscitis.
methodsStudies that evaluated the use of polyetheretherketone (PEEK), titanium, allograft, and/or autologous bone grafts for spondylodiscitis were identified in the literature. Radiographic and clinical data were analyzed using a meta-analysis of proportions, with estimated risk and confidence intervals reported for our primary study outcomes.
resultsThirty-two retrospective studies totaling 1088 patients undergoing surgical management of spondylodiscitis with PEEK, TTN, allograft, and autologous bone graft instrumentation were included. There were no differences in fusion rates (p-interaction = 0.55) with rates of fusion of 93.4% with TTN, 98.6% with allograft, 84.2% with autologous bone graft, and 93.9% with PEEK. There were no differences in screw loosening (p-interaction = 0.52) with rates of 0.33% with TTN, 0% with allograft, 1.3% with autologous bone graft, and 8.2% with PEEK. There were no differences in reoperation (p-interaction = 0.59) with rates of 2.64% with TTN, 0% with allograft, 1.69% with autologous bone graft, and 3.3% with PEEK.
conclusionsThis meta-analysis demonstrates that the choice of instrumentation type in the surgical management of spondylodiscitis resulted in no significant differences in rate of radiographic fusion, screw loosening, or reoperation. Future comparative studies to optimize guidelines for the management of spondylodiscitis are needed.
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