Evidence map›Paper›PMID 38148095›Full record

ArticleIn vivo (Athens, Greece)

[

Yutaro Kubota, Toshihiko Sato, Qinghong Han, Chihiro Hozumi, Sei Morinaga, Kohei Mizuta, Takuya Tsunoda, Robert M Hoffman

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yutaro KubotaAntiCancer Inc., San Diego, CA, U.S.A.
Toshihiko SatoUtsunomiya Central Clinic, Tochigi, Japan.
Qinghong HanAntiCancer Inc., San Diego, CA, U.S.A.
Chihiro HozumiAntiCancer Japan Inc., Narita, Japan.
Sei MorinagaAntiCancer Inc., San Diego, CA, U.S.A.
Kohei MizutaAntiCancer Inc., San Diego, CA, U.S.A.
Takuya TsunodaDivision of Internal Medicine, Department of Medical Oncology, Showa University School of Medicine, Tokyo, Japan.
Robert M HoffmanAntiCancer Inc., San Diego, CA, U.S.A.; all@anticancer.com.
AntiCancer (United States) · USUniversity of California, San Diego · USJapanese Red Cross Narita Hospital · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMethionine addiction is a fundamental and universal hallmark of cancer, termed the Hoffman effect. Methionine addiction of cancer is greater than glucose addiction, termed the Warburg effect, as shown by the comparison of PET imaging with [ PATIENTS AND

methodsIn the present study a patient with invasive lobular carcinoma of the breast metastatic to axillary lymph nodes was imaged by both MET-PET and [

resultsMET-PET gave a much stronger and precise image of the patient's metastatic axillary lymph nodes than FDG-PET. The patient had a complete response to methionine restriction-based chemotherapy as shown by MET-PET.

conclusionMET-PET imaging is a biomarker of methionine-addicted cancer and potential response to methionine-restriction-based chemotherapy.

Indexed as

Breast NeoplasmsMethionineBiomarkers, TumorDrug Therapy, CombinationFemaleFluorodeoxyglucose F18HumansPositron-Emission TomographyRacemethionineRadiopharmaceuticalsBiomarkers, TumorFluorodeoxyglucose F18MethionineRacemethionineRadiopharmaceuticals[11C]methionineCancerchemotherapycombinationHoffman effectmethioninasemethionine addictionmethionine restrictionPET imaging

Identifiers

PMID38148095
PMCPMC10756438
OpenAlexW4390233730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.