Evidence map›Paper›PMID 38147792›Full record

ArticleNeuroImage. Clinical2024

Assessing network degeneration and phenotypic heterogeneity in genetic frontotemporal lobar degeneration by decoding FDG-PET.

Nick Corriveau-Lecavalier, Leland R Barnard, Scott A Przybelski, Venkatsampath Gogineni, Hugo Botha, Jonathan Graff-Radford, Vijay K Ramanan, Leah K Forsberg, Julie A Fields, Mary M Machulda and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 2 countries.

Nick Corriveau-LecavalierDepartment of Neurology, Mayo Clinic Rochester, USA; Department of Psychiatry and Psychology, Mayo Clinic Rochester, USA.
Leland R BarnardDepartment of Neurology, Mayo Clinic Rochester, USA.
Scott A PrzybelskiDepartment of Quantitative Health Sciences, Mayo Clinic Rochester, USA.
Venkatsampath GogineniDepartment of Neurology, Mayo Clinic Rochester, USA.
Hugo BothaDepartment of Neurology, Mayo Clinic Rochester, USA.
Jonathan Graff-RadfordDepartment of Neurology, Mayo Clinic Rochester, USA.
Vijay K RamananDepartment of Neurology, Mayo Clinic Rochester, USA.
Leah K ForsbergDepartment of Neurology, Mayo Clinic Rochester, USA.
Julie A FieldsDepartment of Psychiatry and Psychology, Mayo Clinic Rochester, USA.
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic Rochester, USA.
Rosa RademakersDepartment of Neuroscience, Mayo Clinic Jacksonville, USA; VIB-UA Center for Molecular Neurology, VIB, University of Antwerp, Belgium.
Ralitza H GavrilovaDepartment of Medical Genetics, Mayo Clinic Rochester, USA.
Maria I LapidDepartment of Psychiatry and Psychology, Mayo Clinic Rochester, USA.
Bradley F BoeveDepartment of Neurology, Mayo Clinic Rochester, USA.
David S KnopmanDepartment of Neurology, Mayo Clinic Rochester, USA.
Val J LoweDepartment of Radiology, Mayo Clinic Rochester, USA.
Ronald C PetersenDepartment of Neurology, Mayo Clinic Rochester, USA.
Clifford R JackDepartment of Radiology, Mayo Clinic Rochester, USA.
Kejal KantarciDepartment of Radiology, Mayo Clinic Rochester, USA.
David T JonesDepartment of Neurology, Mayo Clinic Rochester, USA; Department of Radiology, Mayo Clinic Rochester, USA. Electronic address: jones.david@mayo.edu.
Mayo Clinic · USMayo Clinic in Florida · USUniversity of Antwerp · BE

Funding

Technology and Remote Assessment CoreU19AG063911 · NIA · MAYO CLINIC ROCHESTER · PI ADAM L. BOXER, Bradley F Boeve · 2019 to 2026
$120.9M
SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
UC Irvine Alzheimer's Disease Research Center Induced Pluripotent Stem Cell CoreP50AG016573 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI LAFERLA, FRANK M · 2000 to 2019
$37.0M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI Walter K. Kremers · 2019 to 2026
$33.5M
Disease pathways in the population determined by amyloid, tau, and neurodegeneration imaging biomarkersR37AG011378 · NIA · MAYO CLINIC ROCHESTER · PI CLIFFORD R. JACK · 2018 to 2026
$6.8M
Validating the New Criteria for Preclinical Alzheimer's diseaseR01AG041851 · NIA · MAYO CLINIC ROCHESTER · PI JACK, CLIFFORD R., KNOPMAN, DAVID S · 2012 to 2021
$6.3M
NIA NIH HHS P30 AG062677NIA NIH HHS P50 AG016573NIA NIH HHS R01 AG041851NIA NIH HHS R37 AG011378NIA NIH HHS U01 AG006786NIA NIH HHS U19 AG063911
6 · The paper itself

Abstract

Genetic mutations causative of frontotemporal lobar degeneration (FTLD) are highly predictive of a specific proteinopathy, but there exists substantial inter-individual variability in their patterns of network degeneration and clinical manifestations. We collected clinical and

Indexed as

Frontotemporal DementiaFrontotemporal Lobar DegenerationFluorodeoxyglucose F18HumansIntercellular Signaling Peptides and ProteinsMutationPhenotypePositron-Emission TomographyProgranulinsFluorodeoxyglucose F18Intercellular Signaling Peptides and ProteinsProgranulinsClinical neurologyFDG-PETFrontotemporal dementiaFrontotemporal lobar degenerationMachine learning

Identifiers

PMID38147792
PMCPMC10944211
OpenAlexW4390102297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.