Evidence map›Paper›PMID 38147560›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Contingency, repeatability, and predictability in the evolution of a prokaryotic pangenome.

Alan J S Beavan, Maria Rosa Domingo-Sananes, James O McInerney

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Cooperation and the evolution of bacterial niche breadth.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. PanForest: predicting genes in genomes using random forests.Bioinformatics (Oxford, England) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. A phylogenetic approach to comparative genomics.Nature reviews. Genetics · 2025
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alan J S BeavanSchool of Life Sciences, The University of Nottingham, Nottingham NG7 2UH, United Kingdom.ORCID 0000-0002-8219-6742
Maria Rosa Domingo-SananesSchool of Life Sciences, The University of Nottingham, Nottingham NG7 2UH, United Kingdom.ORCID 0000-0002-3339-8671
James O McInerneySchool of Life Sciences, The University of Nottingham, Nottingham NG7 2UH, United Kingdom.ORCID 0000-0003-1885-2503

Funding

UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y513374/1
6 · The paper itself

Abstract

Pangenomes exhibit remarkable variability in many prokaryotic species, much of which is maintained through the processes of horizontal gene transfer and gene loss. Repeated acquisitions of near-identical homologs can easily be observed across pangenomes, leading to the question of whether these parallel events potentiate similar evolutionary trajectories, or whether the remarkably different genetic backgrounds of the recipients mean that postacquisition evolutionary trajectories end up being quite different. In this study, we present a machine learning method that predicts the presence or absence of genes in the

Indexed as

Escherichia coliGenome, BacterialBacteriaEvolution, MolecularPhylogenyProkaryotic Cellsevolutionmachine learningpangenomes

Identifiers

PMID38147560
PMCPMC10769857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.