Evidence map›Paper›PMID 38147215›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Detection of Protein Tyrosine Phosphatase Interacting Partners by Mass Spectrometry.

Martina Samiotaki, George Panayotou, Panagiotis Chandris

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Martina SamiotakiInstitute for Bioinnovation, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
George PanayotouInstitute for Bioinnovation, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Panagiotis ChandrisInstitute for Bioinnovation, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece. chandris@fleming.gr.
Alexander Fleming Biomedical Sciences Research Center · GRPasteur Hellenic Institute · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unraveling interacting partners of protein tyrosine (Tyr) phosphatases is considered a key aspect in resolving the regulation of signaling cascades either in a pathological or in developmental context. Mass spectrometry (MS)-based protein identification has emerged as the major approach in this arena, complemented by the development of novel biochemical methodologies for sample preparation. In this chapter, we highlight two methods that, combined with mass spectrometry, may help the investigator create an interactome map for the phosphatase of interest within a specific biological context.

Indexed as

Protein Tyrosine PhosphatasesSignal TransductionHumansMass SpectrometryProto-Oncogene MasResearch PersonnelProtein Tyrosine PhosphatasesProto-Oncogene MasAPEX2InteractomeMass spectrometryProtein–protein interactionsProximity labelingTyrosine phosphatases

Identifiers

PMID38147215
OpenAlexW4390236096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.