Evidence map›Paper›PMID 38147162›Full record

ArticleChemical senses2024

Sucrose, NaCl, and citric acid suppress the metallic sensation of FeSO4.

Sasi Tansaraviput, Alissa A Nolden

Open access · bronzeAbstract read
In one paragraph

Article in Chemical senses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sasi TansaraviputDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, United States.ORCID 0000-0003-1456-5072
Alissa A NoldenDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, United States.ORCID 0000-0001-9525-5580
University of Massachusetts Amherst · US

Funding

Plasticity of sweet taste: importance of diet and receptor expression in taste budsR21DC018906 · NIDCD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI NOLDEN, ALISSA ALLEN · 2021 to 2023
$465k
NIDCD NIH HHS R21 DC018906NIH HHS DC018906
6 · The paper itself

Abstract

Metallic sensation is often described as unpleasant and can reduce acceptance of foods and beverages and compliance with medication. Masking and suppressing aversive sensations can help to improve acceptance of these products, with many successful strategies identified for bitterness. However, there are few studies investigating effective strategies for suppressing metallic sensation. This study aims to assess the effectiveness of mixture suppression to reduce the metallic sensation elicited from ferrous sulfate and examine whether individual differences in metallic sensation are associated with the effectiveness of suppression strategies. To achieve this, participants (n = 121) reported the intensity of suprathreshold concentrations of ferrous sulfate alone and in binary mixtures with three tastants, specifically, sucrose, citric acid, and sodium chloride. The results revealed that metallic sensation ratings were significantly lower for every binary mixture tested compared to ferrous sulfate presented in isolation. For 0.3 mM ferrous sulfate, sucrose was identified to be the most effective compound in suppressing metallic sensation, followed by citric acid and sodium chloride. For the 1.0 mM ferrous sulfate solutions, all tastants were equally effective at suppressing metallic sensation. In addition, there is a significant interaction between the perceived metallic intensity and the effectiveness of each strategy. These findings suggest that sucrose, citric acid, and sodium chloride have the potential to be effective in suppressing metallic sensation.

Indexed as

Citric AcidFerrous CompoundsSodium ChlorideHumansSensationSucroseTasteCitric AcidFerrous Compoundsferrous sulfateSodium ChlorideSucroseferrous sulfatemaskingmixture suppressionsaltysoursweet

Identifiers

PMID38147162
PMCPMC10808002
OpenAlexW4390227212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.