Evidence map›Paper›PMID 38146973›Full record

ArticleIndian journal of ophthalmology2024

Recurrent and chronic anterior uveitis: Long-term outcome and treatment strategies.

Yael Sharon, Lee Goren, Edward Barayev, Ron Neumann, David S Chu, Michal Kramer

Abstract readMulticenter Study
In one paragraph

Article in Indian journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yael SharonDepartment of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
Lee GorenDepartment of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
Edward BarayevDepartment of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
Ron NeumannMaccabi Health Care Services, Tel Aviv, Israel.
David S ChuMetropolitan Eye Research and Surgery Institute, Palisades Park, New Jersey, USA.
Michal KramerDepartment of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the long-term clinical outcome and treatment strategies of recurrent and chronic non-infectious anterior uveitis.

methodsMulticenter study of anterior uveitis patients from 2001 to 2022. Outcome measures included ocular complications, medical and surgical therapies, and visual acuity measured at the beginning of follow-up and at 1, 2, and 5 years thereafter.

resultsIn total, 76 patients were included, with a mean follow-up of 6.8 years. Idiopathic anterior uveitis was the most common etiology (56%). Immunomodulatory agents (IMAs) were used in almost half of the cohort. Early initiation of IMAs was associated with a lower risk of developing glaucoma ( P = 0.019). Mean best corrected visual acuity (BCVA) improved after 5 years in both groups. Early use of immunomodulation was correlated with a better visual outcome at 2 years ( P = 0.024).

conclusionChronic and recurrent anterior uveitis were associated with greater risk than expected for ocular complications, surgeries, and vision impairment. Early initiation of immunomodulation should be strongly considered to improve clinical course and outcome.

Indexed as

GlaucomaUveitisUveitis, AnteriorChronic DiseaseFollow-Up StudiesHumansRetrospective StudiesTreatment Outcome

Identifiers

PMID38146973
PMCPMC11624633

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.