Evidence map›Paper›PMID 38146612›Full record

ArticleCancer reports (Hoboken, N.J.)2023

Treatment adherence in retinoblastoma: A retro-prospective cohort study in Ivory Coast and the Democratic Republic of Congo.

Robert Mbuli Lukamba, Aléine Nzazi Budiongo, Ben Bondo Monga, Atteby Yao, Pierre Bey, Gabrielle Borasisi Chenge, Laurence Desjardins, François Doz, Albert Tambwe Mwembo, Théophille Amani Kabesha and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Robert Mbuli LukambaDepartment of Pediatrics (Pediatric Oncology Unit), University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo (DRC).ORCID https://orcid.org/0000-0001-6309-4049
Aléine Nzazi BudiongoDepartment of Pediatrics (Pediatric Oncology Unit), University of Kinshasa, Kinshasa, Democratic Republic of the Congo (DRC).
Ben Bondo MongaFaculty of Medicine and School of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo (DRC).
Atteby YaoPediatric Oncology Unit, University Teaching Hospital of Treichville, Abidjan, Ivory Coast.
Pierre BeyAdvisor to the President of Institut Curie, University of Lorraine and AMCC, Paris, France.
Gabrielle Borasisi ChengeOphthalmology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo (DRC).
Laurence DesjardinsOphthalmology Service, Institut Curie and AMCC, Paris, France.
François DozSIREDO Oncology Center (Care, Innovation, Research in Child Oncology, Adolescent and Young Adult) Institut Curie and University Paris Cité, Paris, France.
Albert Tambwe MwemboFaculty of Medicine and School of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo (DRC).
Théophille Amani KabeshaBukavu Ophthalmic Clinic, Bukavu Official University, Bukavu, Democratic Republic of the Congo (DRC).
Oscar Numbi LuboyaDepartment of Pediatrics and School of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo (DRC).
University of Lubumbashi · CDInstitut Curie · FRUniversité Officielle de Bukavu · CDUniversité Paris Cité · FRUniversity Hospital Medical Center at Treichville · CIUniversity of Kinshasa · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn high-income countries, retinoblastoma is curable in more than 95% of cases, whereas in low-income countries, mortality remains high, especially when the diagnosis is made late or the treatment is discontinued.

aimsTo determine the factors associated with adherence to the treatment of retinoblastoma in the Ivory Coast and the Democratic Republic of Congo (DRC). METHODS AND

resultsA retro-prospective cohort study was carried out. Data were collected from patient folders and follow-up records of parents.

resultsA total of 175 children with retinoblastoma were registered from January 2013 to December 2015. Seventy-six children (43%) were 5 years old and above. Care costs were covered by families in 86.9% of cases. Chemotherapy refusal was recorded in 39 cases (22.3%), and enucleation refusal was recorded in 79 cases (45.1%). After 36 months of follow-up, we recorded 16.6% deaths, 27.4% treatment dropouts, and 18.3% loss to follow-up after treatment. The commonest cause for enucleation refusal was fear of infirmity, while chemotherapy refusal and absconding treatment were due to financial constraints.

conclusionPoor adherence to retinoblastoma management was due to financial constraints, and a lack of knowledge of the disease and its treatment. Family psychosocial support is needed to improve this condition.

Indexed as

DRC (Democratic Republic of Congo)Ivory Coastretinoblastomatreatment adhesion

Identifiers

PMID38146612
PMCPMC10849925
OpenAlexW4390235275

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.