ArticleJournal of inflammation research2023
Neutrophil Percentage-to-Albumin Ratio and Risk of Mortality in Patients on Peritoneal Dialysis.
Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictive Value of Machine Learning for Poststroke Mortality Risk: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- The inflammation-nutrition axis and survival outcomes: Role of the neutrophil percentage-to-albumin ratio in patients with sleep disorders.The Journal of international medical research · 2026Article
- Article
- J-shaped association between the neutrophil percentage-to-albumin ratio (NPAR) and depression: analyses of NHANES 2005-2018.European archives of psychiatry and clinical neuroscience · 2026Article
- Association Between Neutrophil Percentage-to-Albumin Ratio (NPAR) and Risk of Stroke in Patients With Hypertension: A Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Establishment and evaluation of a novel tool based on inflammation-nutrition derived biomarkers for early diagnosis of diabetic foot ulcers.Frontiers in immunology · 2026Article
- Neutrophil Percentage-to-Albumin Ratio: Unveiling a New Perspective on Mortality Risk in Intensive Care Unit Asthma Patients-A Retrospective Cohort Study.Mediators of inflammation · 2026Article
- An interpretable machine learning model for predicting distant organ metastasis after radical resection of colorectal cancer.Frontiers in oncology · 2026Article
- Neutrophil Percentage-to-Albumin Ratio as a Predictor of Urinary Tract Infection in Patients with Urinary Stone Disease: Development a Novel User-Friendly Tool.Journal of inflammation research · 2026Article
- Association between the neutrophil-to-albumin ratio and mortality in patients undergoing tracheal intubation: a retrospective cohort study.Frontiers in medicine · 2026Article
- Association Between Neutrophil Percentage to Albumin Ratio and Disease Activity in Hospitalized Patients with Rheumatoid Arthritis: A Cross-Sectional Study.Journal of inflammation research · 2026Article
- Neutrophil-to-lymphocyte ratio as a harbinger of peritonitis in peritoneal dialysis: a case-control study.Frontiers in medicine · 2026Article
- Epidemiological and transcriptome data identify potential key genes involved in inflammatory response for diabetic nephropathy.Scientific reports · 2025Article
- Article
- Predictive value of creatinine-cystatin C ratio for mortality and technique failure in anuric peritoneal dialysis patients.Renal failure · 2025Article
- Article
- Association between neutrophil percentage to albumin ratio and cardiovascular disease in the metabolic syndrome population.Scientific reports · 2025Article
- Association between Neutrophil Percentage-to-Albumin ratio and anemia risk: a population-based study.Scientific reports · 2025Article
- Neutrophil Percentage-to-Albumin Ratio as a Prognostic Marker in Pneumonia Patients Aged 80 and Above in Intensive Care.Journal of clinical medicine · 2025Article
- Biomarker-guided strategy for Denver peritoneovenous shunts in refractory ascites: a retrospective single-center study.Langenbeck's archives of surgery · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Neutrophil percentage-to-albumin ratio (NPAR), a new inflammatory marker, has been shown to be associated with poor prognosis in patients with cardiovascular disease. However, limited evidence is available for its role in peritoneal dialysis (PD) patients. Our study aimed at investigating the prognostic value of NPAR for mortality in PD patients. Patients and Methods: This was a single center retrospective cohort study. A total of 1966 PD patients were enrolled in our study from January 2006 to December 2016 and were followed up until December 2021. Patients were stratified into tertiles according to baseline NPAR levels. The associations between NPAR levels with all-cause and cardiovascular mortality were estimated using Cox proportional hazards models. Receiver operating characteristic (ROC) analysis was performed to compare the mortality predictive values of NPAR and other known biomarkers, such as NLR (neutrophil-to-lymphocyte ratio), PLR (platelet-to-lymphocyte ratio), LHR (low-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio) and MLR (monocyte-to-lymphocyte ratio). Results: During a median follow-up of 48.1 months, 503 (25.6%) patients died, in which cardiovascular disease (CVD) death dominated 50.3%. Multivariate Cox regression analysis revealed that the highest NPAR tertile was significantly associated with a higher risk of all-cause and cardiovascular mortality (HR 1.51, 95% CI 1.14-1.98; HR 1.57, 95% CI 1.07-2.31; respectively) compared with tertile 1. The AUC values of NPAR were 0.62 (95% CI 0.60-0.65, P < 0.001) for all-cause mortality and 0.61 (95% CI 0.57-0.65, P < 0.001) for cardiovascular mortality. Conclusion: Our study showed that higher NPAR levels were independently associated with increased risk of all-cause and cardiovascular mortality in PD patients. Notably, our results demonstrated that NPAR exhibited superior predictive value for mortality compared to NLR, PLR, MLR, and LHR.
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