Evidence map›Paper›PMID 38145728›Full record

ArticleEnvironmental research2024

Prenatal exposure to air pollution and BWGA Z-score: Modifying effects of placenta leukocyte telomere length and infant sex.

Xueying Zhang, Elena Colicino, Whitney Cowell, Michelle Bosquet Enlow, Itai Kloog, Brent A Coull, Joel D Schwartz, Robert O Wright, Rosalind J Wright

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Xueying ZhangDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Kravis Children's Hospital, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: xueying.zhang@mssm.edu.
Elena ColicinoDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Whitney CowellDepartment of Pediatrics, Grossman School of Medicine, New York University, New York, NY, USA.
Michelle Bosquet EnlowDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Itai KloogDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beersheba, Israel.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Joel D SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Robert O WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Kravis Children's Hospital, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Kravis Children's Hospital, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mount Sinai Hospital · USHarvard University · USBen-Gurion University of the Negev · ILBoston Children's Hospital · USIcahn School of Medicine at Mount Sinai · USNew York University · US

Funding

Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUG3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CARROLL, KECIA NICOLE, WRIGHT, ROBERT O · 2016 to 2024
$20.6M
Perinatal Programming of Infant Stress Reactivity and the Atopic PhenotypeR01HL095606 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOSQUET ENLOW, MICHELLE A, WRIGHT, ROSALIND J · 2010 to 2013
$3.1M
Prenatal stress and epigenetic programming of the HPA axis and autonomic balanceR01HL114396 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2012 to 2015
$2.8M
Methods for Data Integration and Risk Assessment for Environmental MixturesR01ES028811 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI COULL, BRENT ANDREW, GENNINGS, CHRIS · 2018 to 2021
$1.9M
Prenatal diet, PM2.5 and programming of the infant autonomic responseR21ES021318 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2012 to 2014
$502k
NCATS NIH HHS UL1 TR004419NHLBI NIH HHS R01 HL095606NHLBI NIH HHS R01 HL114396NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES028811NIEHS NIH HHS R21 ES021318NIH HHS UG3 OD023337NIH HHS UH3 OD023337
6 · The paper itself

Abstract

backgroundAir pollutants, such as fine particulate matter (PM

methodUsing data from a Northeastern U.S. birth cohort (n = 306), we employed linear regression and weighted quantile sum models to assess trimester-average air pollution exposures and birth weight for gestational age (BWGA) z-scores. Placental TL, categorized by median split, was considered as an effect modifier. Interactions among air pollutants, placental TL, infant sex, and BWGA z-score were evaluated.

resultsWithout placental TL as a modifier, only 1

conclusionThese findings highlight the need to consider the complex interactions among prenatal air pollutant exposures, placental TL, and fetal sex to better elucidate those at greatest risk for adverse birth outcomes.

Indexed as

Air PollutantsAir PollutionPrenatal Exposure Delayed EffectsFemaleHumansInfantMaleMaternal ExposureNitrogen DioxideParticulate MatterPlacentaPregnancyTelomereAir PollutantsNitrogen DioxideParticulate MatterAir pollutionBirth outcomesEffect modificationInfant sexPrenatalTelomere length

Identifiers

PMID38145728
PMCPMC12206472
OpenAlexW4390146526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.