Evidence map›Paper›PMID 38145348›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Multiplexed Surface Electrode Arrays Based on Metal Oxide Thin-Film Electronics for High-Resolution Cortical Mapping.

Horacio Londoño-Ramírez, Xiaohua Huang, Jordi Cools, Anna Chrzanowska, Clément Brunner, Marco Ballini, Luis Hoffman, Soeren Steudel, Cédric Rolin, Carolina Mora Lopez and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. A Thin Film Transistor Backplane for Scalable Chronic Neural Interfaces.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Horacio Londoño-RamírezDepartment of Neuroscience, Leuven Brain Institute, Katholieke Universiteit (KU) Leuven, Leuven, 3001, Belgium.ORCID 0000-0003-3456-8975
Xiaohua Huangimec, Leuven, 3001, Belgium.ORCID 0000-0003-4150-0477
Jordi CoolsNeuroelectronics Research Flanders (NERF), Leuven, 3001, Belgium.ORCID 0000-0001-8798-8135
Anna ChrzanowskaNeuroelectronics Research Flanders (NERF), Leuven, 3001, Belgium.ORCID 0000-0002-6166-018X
Clément BrunnerDepartment of Neuroscience, Leuven Brain Institute, Katholieke Universiteit (KU) Leuven, Leuven, 3001, Belgium.ORCID 0000-0002-2567-4832
Marco Balliniimec, Leuven, 3001, Belgium.ORCID 0000-0001-7442-8497
Luis HoffmanNeuroelectronics Research Flanders (NERF), Leuven, 3001, Belgium.ORCID 0000-0002-1489-3669
Soeren Steudelimec, Leuven, 3001, Belgium.ORCID 0000-0002-4885-3841
Cédric Rolinimec, Leuven, 3001, Belgium.ORCID 0000-0001-5542-8504
Carolina Mora Lopezimec, Leuven, 3001, Belgium.ORCID 0000-0003-4200-0001
Jan GenoeDepartment of Electrical Engineering (ESAT), Katholieke Universiteit (KU) Leuven, Leuven, 3001, Belgium.ORCID 0000-0002-4019-5979
Sebastian HaeslerDepartment of Neuroscience, Leuven Brain Institute, Katholieke Universiteit (KU) Leuven, Leuven, 3001, Belgium.ORCID 0000-0003-4924-7381

Funding

Fonds Wetenschappelijk Onderzoek G097022NKU Leuven C14/21/111
6 · The paper itself

Abstract

Electrode grids are used in neuroscience research and clinical practice to record electrical activity from the surface of the brain. However, existing passive electrocorticography (ECoG) technologies are unable to offer both high spatial resolution and wide cortical coverage, while ensuring a compact acquisition system. The electrode count and density are restricted by the fact that each electrode must be individually wired. This work presents an active micro-electrocorticography (µECoG) implant that tackles this limitation by incorporating metal oxide thin-film transistors (TFTs) into a flexible electrode array, allowing to address multiple electrodes through a single shared readout line. By combining the array with an incremental-ΔΣ readout integrated circuit (ROIC), the system is capable of recording from up to 256 electrodes virtually simultaneously, thanks to the implemented 16:1 time-division multiplexing scheme, offering lower noise levels than existing active µECoG arrays. In vivo validation is demonstrated acutely in mice by recording spontaneous activity and somatosensory evoked potentials over a cortical surface of ≈8×8 mm

Indexed as

Brain MappingCerebral CortexAnimalsElectrocorticographyElectrodes, ImplantedElectronicsMicea-IGZOelectrocorticographyelectrode arraysflexible electronicsthin-film transistorstime-division multiplexingµECoGs

Identifiers

PMID38145348
PMCPMC10933637

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.