Evidence map›Paper›PMID 38145334›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

BioinspiredLLM: Conversational Large Language Model for the Mechanics of Biological and Bio-Inspired Materials.

Rachel K Luu, Markus J Buehler

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Sustainable Materials Design With Multi-Modal Artificial Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Review
  8. The Advanced BioTRIZ Method Based on LTE and MPV.Biomimetics (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Autonomous Self-Evolving Research on Biomedical Data: The DREAM Paradigm.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  14. Review
  15. 3D Printable Biocomposites with Tunable Environmental Degradability.3D printing and additive manufacturing · 2025
    Article
  16. Article
  17. Automating alloy design and discovery with physics-aware multimodal multiagent AI.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel K LuuLaboratory for Atomistic and Molecular Mechanics (LAMM), Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.ORCID 0000-0002-7821-934X
Markus J BuehlerLaboratory for Atomistic and Molecular Mechanics (LAMM), Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.ORCID 0000-0002-4173-9659

Funding

Army Research Office W911NF1920098Army Research Office W911NF2220213MIT-IBM Watson AI LabMIT's Generative AI initiativeNational Science Foundation Graduate Research Fellowship 2141064ONR N00014-19-1-2375ONR N00014-20-1-2189USDA 2021-69012-35978
6 · The paper itself

Abstract

The study of biological materials and bio-inspired materials science is well established; however, surprisingly little knowledge is systematically translated to engineering solutions. To accelerate discovery and guide insights, an open-source autoregressive transformer large language model (LLM), BioinspiredLLM, is reported. The model is finetuned with a corpus of over a thousand peer-reviewed articles in the field of structural biological and bio-inspired materials and can be prompted to recall information, assist with research tasks, and function as an engine for creativity. The model has proven that it is able to accurately recall information about biological materials and is further strengthened with enhanced reasoning ability, as well as with Retrieval-Augmented Generation (RAG) to incorporate new data during generation that can also help to traceback sources, update the knowledge base, and connect knowledge domains. BioinspiredLLM also has shown to develop sound hypotheses regarding biological materials design and remarkably so for materials that have never been explicitly studied before. Lastly, the model shows impressive promise in collaborating with other generative artificial intelligence models in a workflow that can reshape the traditional materials design process. This collaborative generative artificial intelligence method can stimulate and enhance bio-inspired materials design workflows. Biological materials are at a critical intersection of multiple scientific fields and models like BioinspiredLLM help to connect knowledge domains.

Indexed as

Artificial IntelligenceBiomimetic MaterialsEngineeringLanguagebio-inspirationbiological materialsgenerative artificial intelligencehierarchical structureslarge language modelsmechanical properties

Identifiers

PMID38145334
PMCPMC10933662

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.