ReviewRedox biology2024
Health position paper and redox perspectives - Disease burden by transportation noise.
Review in Redox biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07148817 (Impact of Personal Mitigation on Mechanisms Linking Transportation Noise Exposure to Cardiometabolic Disease), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Personal Mitigation on Mechanisms Linking Transportation Noise Exposure to Cardiometabolic Disease
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Exposure-response relationship between transportation noise and cardiovascular disease outcomes: a systematic review and meta-regression analysis.Journal of exposure science & environmental epidemiology · 2026Pooled it
- Road traffic noise exposure and blood DNA methylation at birth and in childhood: An epigenome-wide meta-analysis.Environment international · 2026Pooled it
- Environmental Noise Exposure and Risk of Cancer: A Systematic Review and Meta-Analysis.Current environmental health reports · 2025Pooled it
- Long-term exposure to transportation noise and diabetes mellitus mortality: a national cohort study and updated meta-analysis.Environmental health : a global access science source · 2024Pooled it
- A randomized, double-blind, crossover study of acute low-level night-time road traffic noise: effects on vascular function, sleep, and proteomic signatures in healthy adults.Cardiovascular research · 2026Trial
- [Noise and the heart].Herz · 2026Review
- Modeling human neurodegenerative disorders in Drosophila: strategies and translational opportunities.Molecular biology reports · 2026Review
- Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl-Hemoglobin Redox Pairs In Vitro and In Vivo.Molecules (Basel, Switzerland) · 2026Article
- European Code Against Cancer, 5th edition - outdoor and indoor air pollution and cancer.Molecular oncology · 2026Review
- Expert perspectives on exposure-response functions for urban health policy: Lessons from a UBDPolicy workshop.Environmental research · 2026Review
- Effects of noise exposure and long working hours on oxidative stress levels and high-frequency hearing threshold damage in occupational populations.Frontiers in public health · 2026Article
- Association of road traffic noise exposure with dementia or cognitive impairment - A systematic review of longitudinal cohort studies.PLOS global public health · 2026Article
- Imaging Findings Associated With Socioenvironmental Exposures Inform Mechanisms of Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Spatiotemporal patterns in air pollution and sound in Dhaka, Bangladesh.Scientific reports · 2025Article
- Biomarkers of aging: from molecules and surrogates to physiology and function.Physiological reviews · 2025Review
- Road traffic noise and incident ischemic heart disease, myocardial infarction, and stroke: A systematic review and meta-analysis.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Military aircraft noise and drug administrations in psychiatric patients: Follow-up and in-depth case-time series analysis.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts.European journal of epidemiology · 2025Article
- Global Burden of Disease from Environmental Factors.Annual review of public health · 2025Review
- Environmental Pollutants as Emerging Concerns for Cardiac Diseases: A Review on Their Impacts on Cardiac Health.Biomedicines · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 17 institutions in 8 countries.
Funding
Abstract
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart disease. In contrast, they concluded that the quality of evidence for a link to other diseases was very low to moderate. Since then, several studies on the impact of noise on various diseases have been published. Also, studies investigating the mechanistic pathways underlying noise-induced health effects are emerging. We review the current evidence regarding effects of noise on health and the related disease-mechanisms. Several high-quality cohort studies consistently found road traffic noise to be associated with a higher risk of ischemic heart disease, heart failure, diabetes, and all-cause mortality. Furthermore, recent studies have indicated that road traffic and railway noise may increase the risk of diseases not commonly investigated in an environmental noise context, including breast cancer, dementia, and tinnitus. The harmful effects of noise are related to activation of a physiological stress response and nighttime sleep disturbance. Oxidative stress and inflammation downstream of stress hormone signaling and dysregulated circadian rhythms are identified as major disease-relevant pathomechanistic drivers. We discuss the role of reactive oxygen species and present results from antioxidant interventions. Lastly, we provide an overview of oxidative stress markers and adverse redox processes reported for noise-exposed animals and humans. This position paper summarizes all available epidemiological, clinical, and preclinical evidence of transportation noise as an important environmental risk factor for public health and discusses its implications on the population level.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.