SynthesisPalliative medicine2024
Methodological challenges and potential solutions for economic evaluations of palliative and end-of-life care: A systematic review.
Synthesis in Palliative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Economic evaluations in the palliative and end-of-life care settings: A systematic review of existing evidence, methods and quality.Palliative medicine · 2026Pooled it
- Methodologies and characteristics of studies investigating the cost of the palliative phase of cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Translation, cross-cultural adaptation, and validation of the Caregiver Indirect and Informal Care Cost Assessment Questionnaire for end-of-life care into Spanish.Palliative & supportive care · 2026Article
- Toward a comprehensive research agenda: exploring the health economics of palliative care in Australia.BMC palliative care · 2025Article
- Psychometric properties of the ICECAP-SCM capability-wellbeing measure in specialist palliative care units in Austria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Healthcare professionals' perspectives on assessing selected patient-reported outcome measures in specialist palliative care institutions: a multi-country mixed-methods study.BMC palliative care · 2025Article
- Determining timeframes to death for imminently dying patients: a retrospective cohort study.BMC palliative care · 2025Article
- A core outcome set for best care for the dying person: Results of an international Delphi study and consensus meeting.Palliative medicine · 2025Article
- How, when and why is emotional support delivered using videoconferencing by adult palliative care services successful? A realist synthesis.Palliative care and social practice · 2025Review
- Economic Value of Unpaid Family Caregiver Time Following Hospital Discharge and at End of Life.Journal of pain and symptom management · 2024Article
- Systematic Review of the Cost-Effectiveness of Home-Based Palliative Care Interventions in Patients with Cancer: A Critical Analysis.Cancer management and research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the increasing demand for palliative and end-of-life care, along with the introduction of costly new treatments, there is a pressing need for robust evidence on value. However, comprehensive guidance is missing on methods for conducting economic evaluations in this field.
aimTo identify and summarise existing information on methodological challenges and potential solutions/recommendations for economic evaluations of palliative and end-of-life care.
designWe conducted a systematic review of publications on methodological considerations for economic evaluations of adult palliative and end-of-life care as per our PROSPERO protocol CRD42020148160. Following initial searches, we conducted a two-stage screening process and quality appraisal. Information was thematically synthesised, coded, categorised into common themes and aligned with the items specified in the Consolidated Health Economic Evaluation Reporting Standards statement. DATA SOURCES: The databases Medline, Embase, HTADatabase, NHSEED and grey literature were searched between 1 January 1999 and 5 June 2023.
resultsOut of the initial 6502 studies, 81 were deemed eligible. Identified challenges could be grouped into nine themes: ambiguous and inaccurate patient identification, restricted generalisability due to poor geographic transferability of evidence, narrow costing perspective applied, difficulties defining comparators, consequences of applied time horizon, ambiguity in the selection of outcomes, challenged outcome measurement, non-standardised measurement and valuation of costs as well as challenges regarding a reliable preference-based outcome valuation.
conclusionOur review offers a comprehensive context-specific overview of methodological considerations for economic evaluations of palliative and end-of-life care. It also identifies the main knowledge gaps to help prioritise future methodological research specifically for this field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.