Evidence map›Paper›PMID 38141917›Full record

SynthesisEnvironmental research2024

Prenatal air pollution exposure in relation to the telomere-mitochondrial axis of aging at birth: A systematic review.

Shradha Mishra, Charlotte Van Der Stukken, Stacy Drury, Tim S Nawrot, Dries S Martens

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Environmental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shradha MishraCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
Charlotte Van Der StukkenCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
Stacy DruryDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Tim S NawrotCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium; Department of Public Health & Primary Care, Occupational & Environmental Medicine, Leuven University, Leuven, Belgium.
Dries S MartensCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium. Electronic address: dries.martens@uhasselt.be.
Hasselt University · BEBoston Children's Hospital · US

Funding

Elucidating the measurement of telomeres: Development of a transdisciplinary, high-impact Telomere Research NetworkU24AG066528 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI DRURY, STACY SCHMIDT · 2019 to 2023
$3.0M
NIA NIH HHS U24 AG066528
6 · The paper itself

Abstract

backgroundTelomere length (TL) and mitochondrial DNA (mtDNA) are central markers of vital biological mechanisms, including cellular aging. Prenatal air pollution exposure may impact molecular markers of aging leading to adverse health effects.

objectiveTo perform a systematic review on human population-based studies investigating the association between prenatal air pollution exposure and TL or mtDNA content at birth. METHODOLOGY: Searches were undertaken on PubMed and Web of Science until July 2023. The framework of the review was based on the PRISMA-P guidelines.

resultsNineteen studies studied prenatal air pollution and TL or mtDNA content at birth. Studies investigating TL or mtDNA content measured at any other time or did not evaluate prenatal air pollution were excluded. Twelve studies (including 4381 participants with study sample range: 97 to 743 participants) investigated newborn TL and eight studies (including 3081 participants with study sample range: 120 to 743 participants) investigated mtDNA content at birth. Seven studies focused on particulate matter (PM

conclusionThis review provides initial evidence that prenatal PM

Indexed as

Air PollutionDNA, MitochondrialPrenatal Exposure Delayed EffectsTelomereAgingAir PollutantsFemaleHumansInfant, NewbornMaternal ExposureMitochondriaParticulate MatterPregnancyAir PollutantsDNA, MitochondrialParticulate MatterAir pollutionEarly lifeMitochondrial DNANewbornsPrenatal exposureTelomere length

Identifiers

PMID38141917
PMCPMC10922941
OpenAlexW4390084274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.