Evidence map›Paper›PMID 38141758›Full record

ArticleThe Journal of biological chemistry2024

The P2Y

Shenqi Qian, Yi Shi, Jared Senfeld, Qianman Peng, Jianzhong Shen

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shenqi QianDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi ShiDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA.
Jared SenfeldDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA.
Qianman PengDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA.
Jianzhong ShenDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama, USA. Electronic address: jzs0019@auburn.edu.
Auburn University · USSecond Affiliated Hospital of Zhejiang University · CN

Funding

Non-platelet P2Y Receptor in Vascular Inflammation and ThrombogenesisR01HL125279 · NHLBI · AUBURN UNIVERSITY AT AUBURN · PI SHEN, JIANZHONG · 2017 to 2021
$1.9M
NHLBI NIH HHS R01 HL125279
6 · The paper itself

Abstract

Several P2Y nucleotide receptors have been shown to be involved in the early stage of adipocyte differentiation in vitro and insulin resistance in obese mice; however, the exact receptor subtype(s) and its underlying molecular mechanism in relevant human cells are unclear. Here, using human primary visceral preadipocytes as a model, we found that during preadipocyte-to-mature adipocyte differentiation, the P2Y

Indexed as

AdipogenesisInsulin ResistanceReceptors, Purinergic P2Y2AdipocytesAnimalsCells, CulturedGlucose Transporter Type 4GTP-Binding ProteinsHumansLipolysisMiceMice, Inbred C57BLProtein TransportProto-Oncogene Proteins c-aktSignal TransductionUp-RegulationGlucose Transporter Type 4GTP-Binding ProteinsProto-Oncogene Proteins c-aktReceptors, Purinergic P2Y2adipocytesAKTinsulin resistanceobesityP2Y(2) receptor

Identifiers

PMID38141758
PMCPMC10828443
OpenAlexW4390064540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.