Evidence map›Paper›PMID 38140826›Full record

Trial reportIntegrative cancer therapies

Effect of

Kauanny Vitoria Gurgel Dos Santos, Romeika Lorena Mendes da Silva, Ayane Cristine Alves Sarmento, Kleyton Santos de Medeiros, Renata Lima Pessoa, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas

Open access · goldAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kauanny Vitoria Gurgel Dos SantosFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0003-4679-1840
Romeika Lorena Mendes da SilvaInstitute of Education, Research and Innovation, Liga Contra o Câncer, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0001-7521-1791
Ayane Cristine Alves SarmentoFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0001-9131-1952
Kleyton Santos de MedeirosFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0002-4105-7535
Renata Lima PessoaInstitute of Education, Research and Innovation, Liga Contra o Câncer, Natal, Rio Grande do Norte, Brazil.
Daniele Vieira DantasFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0003-0307-2424
Rodrigo Assis Neves DantasFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0002-9309-2092
Universidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveevaluate the efficacy of Zingiber Officinale in the management of nausea and vomiting induced by treatment with cisplatin associated with radiotherapy in patients with uterine cervical neoplasms.

methodsa triple-blind, randomized, placebo-controlled trial. Interventions: Comparing the effects of ginger with institutional antiemetic therapy (ondansetron with dexamethasone). Patients with cervical cancer who started treatment with cisplatin with an indication of 40 mg/m² associated with radiotherapy, aged over 18 years, and with the ability to tolerate swallowing a capsule were recruited and equally allocated (1:1:1) into 3 groups of 16 patients each (the ginger capsules 250 mg group, ginger capsules 500 mg group, and placebo group). Nausea and vomiting were measured on baseline, 7 days after the first dose of medication and every seven consecutive days during a treatment break.

resultsThe 250 mg ginger group had an 8.0% greater chance of experiencing nausea within 24 h after the chemotherapy infusion than the placebo group, although there is no statistical significance (

conclusionGinger supplementation does not reduce the intensity of acute and late nausea and vomiting. REBEC (RBR-47yx6p9).

Indexed as

Uterine Cervical NeoplasmsZingiber officinaleAdultCisplatinDouble-Blind MethodFemaleHumansMiddle AgedNauseaVomitingCisplatinchemotherapygingernausearadiotherapyuterine cervical neoplasmsvomiting

Identifiers

PMID38140826
OpenAlexW4390143642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.