Evidence map›Paper›PMID 38140658›Full record

ArticleViruses2023

Respiratory Syncytial Virus Reinfections in Children in Western Australia.

David A Foley, Cara A Minney-Smith, Wei Hao Lee, Daniel B Oakes, Briony Hazelton, Timothy J Ford, Ushma Wadia, Chisha Sikazwe, Hannah C Moore, Mark P Nicol and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

David A FoleyDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.ORCID 0000-0002-8622-7809
Cara A Minney-SmithDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.
Wei Hao LeeSchool of Medicine, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-1212-1286
Daniel B OakesWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-4671-1599
Briony HazeltonDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.ORCID 0000-0002-3101-5390
Timothy J FordSchool of Medicine, University of Western Australia, Perth, WA 6009, Australia.
Ushma WadiaWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-8097-5072
Chisha SikazweDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.ORCID 0000-0002-1052-9018
Hannah C MooreWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-6434-8290
Mark P NicolWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia.
Avram LevyDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.
Christopher C BlythDepartment of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia.
The Kids Research Institute Australia · AUThe University of Western Australia · AUPathwest Laboratory Medicine · AUPrincess Margaret Hospital for Children · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) reinfection in children is poorly understood. We examined the incidence, characteristics, and outcomes of hospital-attended RSV reinfections in children <16 years in Western Australia between 2012 and 2022. Individuals with repeat RSV detections ≥56 days apart were identified using laboratory data. The incidence of reinfection in the first five years of life was estimated using the total birth population from 2012 to 2017. Clinical data on a subset of reinfection episodes were obtained from two metropolitan pediatric centers. A total of 466 children with hospital-attended reinfections were identified. The median interval between RSV detections was 460 days (interquartile range: 324, 812), with a reinfection rate of 95 per 100,000 individuals (95% confidence interval: 82, 109). Reinfection was most common in children who experienced their first RSV detection <6 months of age. Predisposing factors were identified in 56% of children; children with predisposing factors were older at first and second detections, were more likely to be admitted, and had a longer length of stay. This study highlights the significant burden of hospital-attended RSV reinfections in children with and without predisposing factors. Expanded surveillance with in-depth clinical data is required to further characterize the impact of RSV reinfection.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsChildHospitalizationHumansInfantReinfectionWestern Australiachildrenimmunityreinfectionrespiratory syncytial virusrespiratory virus

Identifiers

PMID38140658
PMCPMC10747877
OpenAlexW4389673971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.